Glitazone Treatment and Incidence of Parkinson’s Disease among People with Diabetes: A Retrospective Cohort Study

Brauer, R; Bhaskaran, KORCID logo; Chaturvedi, N; Dexter, DT; Smeeth, LORCID logo and Douglas, IORCID logo (2015). Glitazone Treatment and Incidence of Parkinson’s Disease among People with Diabetes: A Retrospective Cohort Study. [Dataset]. PLOS Medicine. https://doi.org/10.1371/journal.pmed.1001854.s002
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Study instruments supporting a retrospective cohort study that explored potential links between prescription of anti-diabetic glitazone (GTZ) drugs and incidence of Parkinson’s disease. Outputs include: information on patient demographics and characteristics; codes used to identify GTZ exposure; codes used to identify Parkinson’s disease; variable code listings; a checklist of items to be included in cohort study reports; an ISAC application form; and a CPRD research protocol.

Keywords

Retrospective Cohort Study; PPAR gamma pathways; Prescription; Parkinson's disease diagnosis; Incidence rate ratio; GTZ; Antidiabetic; Diabetes treatment stage; Glitazone

Data / Code

S1_Table-CSV.csv
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Data
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Patient demographics and characteristics: Individuals diagnosed with PD versus individuals not diagnosed with PD
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S1_Table-MSWord.doc
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Data
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Patient demographics and characteristics: Individuals diagnosed with PD versus individuals not diagnosed with PD
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Documentation

S1_Text.pdf
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Documentation
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Codes used to identify GTZ exposure
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S2_Text.pdf
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Documentation
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Codes used to identify PD: PD with no identified cause and PD with identified causes
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S3_Text.docx
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Documentation
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Codes used for variables listed in Table 1
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Study Instrument

S1_Protocol.pdf
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Study Instrument
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ISAC application form - Protocol for research using the CPRD
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S1_STROBE_Checklist.pdf
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Study Instrument
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Checklist of items that should be included in reports of cohort studies
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