Glitazone Treatment and Incidence of Parkinson’s Disease among People with Diabetes: A Retrospective Cohort Study

Brauer, R, Bhaskaran, KORCID logo, Chaturvedi, N, Dexter, DT, Smeeth, LORCID logo and Douglas, IORCID logo (2015). Glitazone Treatment and Incidence of Parkinson’s Disease among People with Diabetes: A Retrospective Cohort Study. [Dataset]. PLOS Medicine. https://doi.org/10.1371/journal.pmed.1001854.s002 https://doi.org/10.1371/journal.pmed.1001854
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Study instruments supporting a retrospective cohort study that explored potential links between prescription of anti-diabetic glitazone (GTZ) drugs and incidence of Parkinson’s disease. Outputs include: information on patient demographics and characteristics; codes used to identify GTZ exposure; codes used to identify Parkinson’s disease; variable code listings; a checklist of items to be included in cohort study reports; an ISAC application form; and a CPRD research protocol.

Keywords

Retrospective Cohort Study, PPAR gamma pathways, Prescription, Parkinson's disease diagnosis, Incidence rate ratio, GTZ, Antidiabetic, Diabetes treatment stage, Glitazone

S1_Protocol.pdf
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Study Instrument
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ISAC application form - Protocol for research using the CPRD
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S1_STROBE_Checklist.pdf
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Study Instrument
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Checklist of items that should be included in reports of cohort studies
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S1_Table-CSV.csv
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Data
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Patient demographics and characteristics: Individuals diagnosed with PD versus individuals not diagnosed with PD
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S1_Table-MSWord.doc
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Data
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Patient demographics and characteristics: Individuals diagnosed with PD versus individuals not diagnosed with PD
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S1_Text.pdf
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Documentation
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Codes used to identify GTZ exposure
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S2_Text.pdf
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Documentation
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Codes used to identify PD: PD with no identified cause and PD with identified causes
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S3_Text.docx
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Documentation
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Codes used for variables listed in Table 1
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