Ebola virus disease in the Democratic Republic of the Congo, 1976-2014: Figures and Data

Rosello, AORCID logo, Mossoko, M, Flasche, SORCID logo, Vanhoek, A, Mbala, P, Camacho, AORCID logo, Funk, SORCID logo, Kucharski, AORCID logo, Ilunga, BK, Edmunds, JORCID logo, Piot, P, Baguelin, MORCID logo and Tamfum, JM (2015). Ebola virus disease in the Democratic Republic of the Congo, 1976-2014: Figures and Data. [Data Collection]. London School of Hygiene & Tropical Medicine, London, United Kingdom. 10.17037/DATA.30.
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The Democratic Republic of the Congo has experienced the most outbreaks of Ebola virus disease since the virus' discovery in 1976. This dataset contains details on all outbreaks in this country, comprising 996 cases. The study found that, compared to patients over 15 years old, the odds of dying were significantly lower in patients aged 5 to 15 and higher in children under five (with 100% mortality in those under 2 years old). The odds of dying increased by 11% per day that a patient was not hospitalised. Outbreaks with an initially high reproduction number, R (>3), were rapidly brought under control, whilst outbreaks with a lower initial R caused longer and generally larger outbreaks. These findings can inform the choice of target age groups for interventions and highlight the importance of both reducing the delay between symptom onset and hospitalisation and rapid national and international response.

Keywords

Ebola, Epidemiology, Democratic Republic of the Congo, Outbreaks

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Aggregated line list for all outbreaks in the Democratic Republic of the Congo. https://doi.org/10.7554/eLife.09015.017
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Aggregated_LineList_tab.txt
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Aggregated line list for all outbreaks in the Democratic Republic of the Congo
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Figure1.jpg
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Map and historical timeline of the EVD outbreaks in the DRC
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Incidence of cases by age and sex in the DRC outbreaks in comparison to the demographics of the national 1975–2010 population
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Time course of the EVD outbreaks in DRC
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Percentage of probable and confirmed cases with abdominal pain, diarrhoea, fever, haemorrhagic symptoms, headache, and vomiting
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Evolving case-fatality ratios with time after the start of the outbreak
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Figure5-supplement1.jpg
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CFR by age groups for each outbreak
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Aggregated CFRs for all outbreaks by age group
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Evolving effective reproduction numbers with time after the start of the outbreak and adjusted weekly incidence
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Delay distributions for the EVD outbreaks in the DRC
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InterventionRepository.pdf
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Repository of the interventions carried out during all outbreaks in the Democratic Republic of the Cong
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Repository of the interventions carried out during all outbreaks in the Democratic Republic of the Congo. https://doi.org/10.7554/eLife.09015.018
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