The data contain anonymized individual-level records of 478 schoolchildren (aged 9-17 years) who participated in a randomized controlled trial investigating the effect of Schistosomiasis treatment on responses to a portfolio of vaccines, known as the POPVAC A trial. Helminth infections were assessed prior to vaccination to enable comparisons of vaccine-specific immune responses between infected and uninfected children, aiming to answer the question of whether helminth infection before vaccination affects responses observed following vaccination.

To access the data, requests must be made to the PI (Professor Alison Elliott). The request will be reviewed by the PI together with the POPVAC investigator team, in consultation with the POPVAC steering committee. The request will be reviewed based on scientific value and to ensure there is no overlap with existing work. If the request is approved, before data is shared, ethics approval will need to be obtained in your host institution and a Data Transfer Agreement with the MRC/UVRI and LSHTM Uganda Research Unit must be completed.

Helminths, vaccination, immune responses