Life tables for global surveillance of cancer survival (the CONCORD programme): data sources and methods
We set out to estimate net survival trends for 10 common cancers in 279 cancer registry populations in 67 countries around the world, as part of the CONCORD-2 study. Net survival can be interpreted as the proportion of cancer patients who survive up to a given time, after eliminating the impact of mortality from other causes (background mortality). Background mortality varies widely between populations and over time. It was therefore necessary to construct robust life tables that accurately reflected the background mortality in each of the registry populations. Life tables of all-cause mortality rates by single year of age and sex were constructed by calendar year for each population and, when possible, by racial or ethnic sub-groups. We used three different approaches, based on the type of mortality data available from each registry. With death and population counts, we adopted a flexible multivariable modelling approach. With unsmoothed mortality rates, we used the Ewbank relational method. Where no data were available from the registry or a national statistical office, we used the abridged UN Population Division life tables and interpolated these using the Elandt-Johnson method. We also investigated the impact of using state- and race-specific life tables versus national race-specific life tables on estimates of net survival from four adult cancers in the United States (US).
Keywords
Life tables, Mortality, Life expectancy, Generalised linear model, Cubic splines, Global health, Net survivalItem Type | Dataset |
---|---|
Capture method | Aggregation |
Date | 27 February 2017 |
Language(s) of written materials | English |
Creator(s) |
Spika, D, Bannon, F, Bonaventure, A, Woods, LM |
LSHTM Faculty/Department | Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology |
Participating Institutions | London School of Hygiene & Tropical Medicine |
Funders |
Project Funder Grant Number Funder URI |
Date Deposited | 06 Mar 2017 12:38 |
Last Modified | 09 Jul 2021 11:22 |
Publisher | Figshare |
Explore Further
- Spika, Devon
- Bannon, Finian
- Bonaventure, Audrey
- Woods, Laura M
- Harewood, Rhea
- Carreira, Helena
- Coleman, Michel P
- Allemani, Claudia
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subject - Documentation
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Additional information on the selection of knot locations for the flexible Poisson model. https://doi.org/10.6084/m9.figshare.c.3704431_D4
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subject - Documentation
- Creative Commons: Attribution
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info - Model for constructing race/ethnic-specific life tables using a continuous interaction term between race and age. https://doi.org/10.6084/m9.figshare.c.3704431_D5
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subject - Documentation
- Creative Commons: Attribution
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info - Example of a life table report. https://doi.org/10.6084/m9.figshare.c.3704431_D1
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subject - Data
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Background mortality in 327 populations covered by 279 registries during 1995–2009. https://doi.org/10.6084/m9.figshare.c.3704431_D2
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subject - Documentation
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Alternative model for constructing race/ethnic-specific life tables using dummy interaction terms. https://doi.org/10.6084/m9.figshare.c.3704431_D3
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