Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations. S1 File
Soremekun, C; Machipisa, T; Soremekun, O; Pirie, F; Oyekanmi, N
; Motala, AA; Chikowore, T and Fatumo, S
(2023).
Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations. S1 File.
[Dataset].
PLOS ONE.
https://doi.org/10.1371/journal.pone.0280344.s001
; Motala, AA; Chikowore, T and Fatumo, S
(2023).
Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations. S1 File.
[Dataset].
PLOS ONE.
https://doi.org/10.1371/journal.pone.0280344.s001
The study sought to identify genetic loci associated with liver biomarker levels with a shared genetic basis, using a multivariate genome-wide association study (GWAS) approach. The dataset contains the results of a joint analysis from two genetically distinct African populations, the Ugandan Genome Resource (UGR = 6,407) and South African Zulu cohort (SZC = 2,598).
Keywords
Genome-wide association Study; Biomarkers; Liver diseases; Single nucleotide polymorphisms; Bilirubin; Genetic loci; Fatty liver; Genetics of disease| Item Type | Dataset |
|---|---|
| Resource Type |
Resource Type Resource Description Dataset Quantitative |
| Capture method | Experiment |
| Date | 21 February 2023 |
| Geographical area covered (offline during plugin upgrade) |
North East South West 3.25839 34.2802 -0.607024 30.6767 -26.6421 31.8193 -34.3566 20.2177 |
| Language(s) of written materials | English |
| Creator(s) |
Soremekun, C; Machipisa, T; Soremekun, O; Pirie, F; Oyekanmi, N; Motala, AA; Chikowore, T and Fatumo, S
|
| LSHTM Faculty/Department |
Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology MRC/UVRI and LSHTM Uganda Research Unit |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda |
| Funders |
Project Funder Grant Number Funder URI |
| Date Deposited | 02 Mar 2023 16:51 |
| Last Modified | 16 Sep 2025 08:34 |
| Publisher | PLOS ONE |
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