Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations. S1 File

Soremekun, C, Machipisa, T, Soremekun, O, Pirie, F, Oyekanmi, NORCID logo, Motala, AA, Chikowore, T and Fatumo, SORCID logo (2023). Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations. S1 File. [Dataset]. PLOS ONE. https://doi.org/10.1371/journal.pone.0280344.s001
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The study sought to identify genetic loci associated with liver biomarker levels with a shared genetic basis, using a multivariate genome-wide association study (GWAS) approach. The dataset contains the results of a joint analysis from two genetically distinct African populations, the Ugandan Genome Resource (UGR = 6,407) and South African Zulu cohort (SZC = 2,598).

Keywords

Genome-wide association Study, Biomarkers, Liver diseases, Single nucleotide polymorphisms, Bilirubin, Genetic loci, Fatty liver, Genetics of disease

Item Type Dataset
Capture method Experiment
Date 21 February 2023
Geographical area covered (offline during plugin upgrade)
North Latitude
East Longitude
South Latitude
West Longitude
3.25839
34.2802
-0.607024
30.6767
-26.6421
31.8193
-34.3566
20.2177
Language(s) of written materials English
Creator(s) Soremekun, C, Machipisa, T, Soremekun, O, Pirie, F, Oyekanmi, NORCID logo, Motala, AA, Chikowore, T and Fatumo, SORCID logo
LSHTM Faculty/Department Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology
MRC/UVRI and LSHTM Uganda Research Unit
Participating Institutions London School of Hygiene & Tropical Medicine, London, United Kingdom, MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda
Funders
Project
Funder
Grant Number
Funder URI
UNSPECIFIED
Wellcome Trust
214205/Z/18/Z
http://dx.doi.org/10.13039/100010269
UNSPECIFIED
Wellcome Trust
220740/Z/20/Z
http://dx.doi.org/10.13039/100010269
Date Deposited 02 Mar 2023 16:51
Last Modified 02 Mar 2023 17:01
Publisher PLOS ONE

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