Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations. S1 File

Soremekun, C; Machipisa, T; Soremekun, O; Pirie, F; Oyekanmi, N

; Motala, AA; Chikowore, T and Fatumo, S

(2023). Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations. S1 File. [Dataset]. PLOS ONE. https://doi.org/10.1371/journal.pone.0280344.s001

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The study sought to identify genetic loci associated with liver biomarker levels with a shared genetic basis, using a multivariate genome-wide association study (GWAS) approach. The dataset contains the results of a joint analysis from two genetically distinct African populations, the Ugandan Genome Resource (UGR = 6,407) and South African Zulu cohort (SZC = 2,598).

Keywords

Genome-wide association Study; Biomarkers; Liver diseases; Single nucleotide polymorphisms; Bilirubin; Genetic loci; Fatty liver; Genetics of disease

Item Type	Dataset
Resource Type	Resource Type Resource Description Dataset Quantitative
Capture method	Experiment
Date	21 February 2023
Geographical area covered (offline during plugin upgrade)	North East South West 3.25839 34.2802 -0.607024 30.6767 -26.6421 31.8193 -34.3566 20.2177
Language(s) of written materials	English
Creator(s)	Soremekun, C; Machipisa, T; Soremekun, O; Pirie, F; Oyekanmi, N; Motala, AA; Chikowore, T and Fatumo, S
LSHTM Faculty/Department	Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology MRC/UVRI and LSHTM Uganda Research Unit
Participating Institutions	London School of Hygiene & Tropical Medicine, London, United Kingdom; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda
Funders	Project Funder Grant Number Funder URI UNSPECIFIED Wellcome Trust 214205/Z/18/Z http://dx.doi.org/10.13039/100010269 UNSPECIFIED Wellcome Trust 220740/Z/20/Z http://dx.doi.org/10.13039/100010269
Date Deposited	02 Mar 2023 16:51
Last Modified	16 Sep 2025 08:34
Publisher	PLOS ONE