DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis
Mowbray, CE
; Braillard, S; Glossop, PA; Whitlock, GA; Jacobs, RT; Speake, J; Pandi, B; Nare, B; Maes, L; Yardley, V; Freund, Y; Wall, RJ; Carvalho, S; Bello, D; Van den Kerkhof, M; Caljon, G; Gilbert, IH; Corpas-Lopez, V; Lukac, I; Patterson, S; Zuccotto, F and Wyllie, S
(2021).
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis.
[Dataset].
ACS Publications, Washington, DC, USA.
https://doi.org/10.1021/acs.jmedchem.1c01437.s004
; Braillard, S; Glossop, PA; Whitlock, GA; Jacobs, RT; Speake, J; Pandi, B; Nare, B; Maes, L; Yardley, V; Freund, Y; Wall, RJ; Carvalho, S; Bello, D; Van den Kerkhof, M; Caljon, G; Gilbert, IH; Corpas-Lopez, V; Lukac, I; Patterson, S; Zuccotto, F and Wyllie, S
(2021).
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis.
[Dataset].
ACS Publications, Washington, DC, USA.
https://doi.org/10.1021/acs.jmedchem.1c01437.s004
DNDI-6148 has been declared a preclinical candidate for the treatment of visceral leishmaniasis. This collection contains documentation (S1), string data for all compounds (S2), DNDI-6148 rat and dog pharmacokinetic data (S3) and Compound 23 docked into LdCPSF3 (S4). Files may be accessed through the Collection Record held on Figshare.
Keywords
Visceral leishmaniasis; Parasitic diseases; Benzoxaborole chemotype; Antileishmanial activity; DNDI-6148| Item Type | Dataset |
|---|---|
| Resource Type |
Resource Type Resource Description Dataset Quantitative |
| Capture method | Unknown |
| Date | 29 October 2021 |
| Language(s) of written materials | English |
| Creator(s) |
Mowbray, CE; Braillard, S; Glossop, PA; Whitlock, GA; Jacobs, RT; Speake, J; Pandi, B; Nare, B; Maes, L; Yardley, V; Freund, Y; Wall, RJ; Carvalho, S; Bello, D; Van den Kerkhof, M; Caljon, G; Gilbert, IH; Corpas-Lopez, V; Lukac, I; Patterson, S; Zuccotto, F and Wyllie, S
|
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Department of Infection Biology |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Funders |
Project Funder Grant Number Funder URI UNSPECIFIED UNSPECIFIED http://dx.doi.org/10.13039/501100002347 UNSPECIFIED UNSPECIFIED http://dx.doi.org/10.13039/100009131 |
| Date Deposited | 18 Nov 2022 11:03 |
| Last Modified | 21 Oct 2025 14:44 |
| Publisher | ACS Publications |
No files available. Please consult associated links.
