DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis
Mowbray, CE
, Braillard, S, Glossop, PA, Whitlock, GA, Jacobs, RT, Speake, J, Pandi, B, Nare, B, Maes, L, Yardley, V, Freund, Y, Wall, RJ, Carvalho, S, Bello, D, Van den Kerkhof, M, Caljon, G, Gilbert, IH, Corpas-Lopez, V, Lukac, I, Patterson, S, Zuccotto, F and Wyllie, S
(2021).
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis.
[Dataset].
ACS Publications, Washington, DC, USA.
https://doi.org/10.1021/acs.jmedchem.1c01437.s004
, Braillard, S, Glossop, PA, Whitlock, GA, Jacobs, RT, Speake, J, Pandi, B, Nare, B, Maes, L, Yardley, V, Freund, Y, Wall, RJ, Carvalho, S, Bello, D, Van den Kerkhof, M, Caljon, G, Gilbert, IH, Corpas-Lopez, V, Lukac, I, Patterson, S, Zuccotto, F and Wyllie, S
(2021).
DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis.
[Dataset].
ACS Publications, Washington, DC, USA.
https://doi.org/10.1021/acs.jmedchem.1c01437.s004
DNDI-6148 has been declared a preclinical candidate for the treatment of visceral leishmaniasis. This collection contains documentation (S1), string data for all compounds (S2), DNDI-6148 rat and dog pharmacokinetic data (S3) and Compound 23 docked into LdCPSF3 (S4). Files may be accessed through the Collection Record held on Figshare.
Keywords
Visceral leishmaniasis, Parasitic diseases, Benzoxaborole chemotype, Antileishmanial activity, DNDI-6148| Item Type | Dataset |
|---|---|
| Capture method | Unknown |
| Date | 29 October 2021 |
| Language(s) of written materials | English |
| Creator(s) |
Mowbray, CE, Braillard, S, Glossop, PA, Whitlock, GA, Jacobs, RT, Speake, J, Pandi, B, Nare, B, Maes, L, Yardley, V, Freund, Y, Wall, RJ, Carvalho, S, Bello, D, Van den Kerkhof, M, Caljon, G, Gilbert, IH, Corpas-Lopez, V, Lukac, I, Patterson, S, Zuccotto, F and Wyllie, S
|
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Department of Infection Biology |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Funders |
Project Funder Grant Number Funder URI UNSPECIFIED UNSPECIFIED http://dx.doi.org/10.13039/501100002347 UNSPECIFIED UNSPECIFIED http://dx.doi.org/10.13039/100009131 |
| Date Deposited | 18 Nov 2022 11:03 |
| Last Modified | 04 Jul 2025 08:47 |
| Publisher | ACS Publications |
No files available. Please consult associated links.
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