Transcription profiling by array of Caenorhabditis elegans with biofilm compared to without biofilm

Comparison of gene expression in C. elegans with biofilm compared to C. elegans without biofilm. Background: Yersinia pseudotuberculosis YpIII strain forms a biofilm on C. elegans. The biofilm develops over a period of hours. Thus, at 1 hour the worm has little actual biofilm but exhibits abnormal movement; at 24 hours the worm has a large mass of biofilm, mostly over anterior end. Yersinia pseudotuberculosis 3384 does not form a biofilm on C. elegans. Yersinia pseudotuberculosis mutant in the ypsR/ytbR locus does not form a biofilm by virtue of having a non-functional quorum sensing system.

Keywords

Gene expression; C. elegans; Yersinia pseudotuberculosis; Caenorhabditis elegans