XPHACTOR Clinical Score dataset

Hanifa, Y, Fielding, KORCID logo, Grant, ADORCID logo and Churchyard, GJ (2016). XPHACTOR Clinical Score dataset. [Dataset]. London School of Hygiene & Tropical Medicine, London, United Kingdom. 10.17037/DATA.204.
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The World Health Organization (WHO) recommendation for regular tuberculosis (TB) screening of HIV-positive individuals with Xpert MTB/RIF as the first diagnostic test has major resource implications. The aim of our study was to develop a score, comprising elements readily available in primary care, to predict probability of TB in adults attending for routine HIV care screened for TB and found WHO tool positive. We used data collected for “Xpert for people attending HIV/AIDS care: test or review?” (XPHACTOR), a prospective cohort study evaluating a risk-based algorithm to prioritise Xpert MTB/RIF testing amongst adults attending for routine HIV care in South Africa, to develop and validate our clinical score. This dataset contains data for 1,048 HIV-positive adults attending for routine HIV care and reporting ≥1 symptom on the WHO screening tool. The dataset is split 50:50 to derive, and internally validate the prediction model. It includes basic demographics, TB diagnoses, and candidate predictors considered for the score. Data was collected for the purpose of HIV and TB research and can only be reused for related research, in accordance with the participant consent agreement.

Additional Information

Data was obtained from study participants on the basis that it would be used for HIV and TB related research. To comply with the study's ethical obligations, the dataset can only be made available on condition that the requester provides details of their research and signs a data sharing agreement.

Keywords

Tuberculosis diagnosis, Development, Validation, South Africa, HIV

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Clinical Score dataset - MS Excel and CSV format. Data can be reused for HIV and TB related research only
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Clinical_score_codebook.html
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