Dataset for: "Comparing patterns of recent and remote Mycobacterium tuberculosis infection determined using the QuantiFERON-TB Gold Plus assay in a high TB burden setting"
Schaap, A
and Amofa-Sekyi, M
(2024).
Dataset for: "Comparing patterns of recent and remote Mycobacterium tuberculosis infection determined using the QuantiFERON-TB Gold Plus assay in a high TB burden setting".
[Dataset].
London School of Hygiene & Tropical Medicine, London, United Kingdom.
10.17037/DATA.00003879.
and Amofa-Sekyi, M
(2024).
Dataset for: "Comparing patterns of recent and remote Mycobacterium tuberculosis infection determined using the QuantiFERON-TB Gold Plus assay in a high TB burden setting".
[Dataset].
London School of Hygiene & Tropical Medicine, London, United Kingdom.
10.17037/DATA.00003879.
Dataset to reproduce the statistical analysis of the patterns of interferon gamma responses in recent and remote infection as measured by the QuantiFERON-TB Gold Plus assay in the TREATS-TB incidence of infection Cohort. Each row represents a randomly selected adolescent or young adult of one of the 14 communities that were included in the cohort but restricted to those defined as recent or remote according to the criteria described in the paper. Apart from the QuantiFERON-TB Gold Plus tube responses, the data includes HIV-status, having a household contact on TB-treatment in the past or currently and demographic characteristics.
Keywords
Tuberculosis infection, IGRA, recent infection, Remote infection, adolescent and young adults| Item Type | Dataset |
|---|---|
| Description of data capture | All household members of randomly selected households were enumerated and eligible adolescents and young adults were invited to a health facility (Zambia) or clinical research site (South Africa) for enrolment. After informed consent. password-protected tablets were used by trained research assistants to record information on socio-demographic data, TB/HIV history, known TB risk factors, and other characteristics via the administration of a structured questionnaire. Rapid HIV-testing was done at the research site and results recorded using the same tablet. Blood samples were taken for QFT-Plus testing. Results of the QuantiFERON Gold Plus assay were afterwards combined with the questionnaire data using the unique (barcoded) identifier of the participant. |
| Capture method | Questionnaire |
| Collection Period |
From To July 2018 January 2021 |
| Date | 10 May 2024 |
| Language(s) of written materials | English |
| Creator(s) |
Schaap, A and Amofa-Sekyi, M
|
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Clinical Research |
| Research Centre | ACT Consortium |
| Participating Institutions | Zambart, Lusaka, Zambia, Health Systems Trust, Cape Town, South Africa, London School of Hygiene & Tropical Medicine, London, United Kingdom, KNCV Tuberculosis Foundation, The Hague, Netherlands, HIV Clinical Trials Unit, Imperial College London, London, United Kingdom |
| Funders |
Project Funder Grant Number Funder URI TREATS RIA2026S-1632 http://dx.doi.org/10.13039/501100001713 |
| Date Deposited | 13 May 2024 10:00 |
| Last Modified | 13 May 2024 10:08 |
| Publisher | London School of Hygiene & Tropical Medicine |
TREATS-ic-recentremote_data.csv
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subject - Data
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- Available under Creative Commons: Attribution 4.0
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info - Anonymised dataset collected for the TREATS TB-infection cohort for recent versus remote analysis
description - text/plain
- folder_info
- 44kB
TREATS-ic-recentremote_data_HIV.txt
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subject - Data
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lock - Restricted to Request access for all
- Data Sharing Agreement
- Available under Data Sharing Agreement
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info - Anonymised dataset containing HIV-status collected for the TREATS TB-infection cohort for recent versus remote analysis
description - text/plain
- folder_info
- 52B
TREATS-ic-recentremote_data_codebook.html
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subject - Documentation
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- Available under Creative Commons: Attribution 4.0
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info - Codebook for the TREATS TB-infection cohort recent versus remote analysis dataset
html - text/html
- folder_info
- 6kB
3879-UserGuide.html
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subject - Documentation
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- Available under Creative Commons: Attribution 4.0
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info - User guide for the TREATS TB-infection cohort recent versus remote analysis dataset
html - text/html
- folder_info
- 5kB
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