Data supporting "Does schistosome or malaria exposure contribute to urban-rural differences in vaccine responses in Uganda? A causal mediation analysis using data from three linked randomised controlled trials."

Natukunda, A, Nkurunungi, G, Zirimenya, L, Nassuuna, J, Elliott, AM and Webb, E. 2024. Data supporting "Does schistosome or malaria exposure contribute to urban-rural differences in vaccine responses in Uganda? A causal mediation analysis using data from three linked randomised controlled trials.". [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: https://doi.org/10.17037/DATA.00003761.

Natukunda, A, Nkurunungi, G, Zirimenya, L, Nassuuna, J, Elliott, AM and Webb, E. Data supporting "Does schistosome or malaria exposure contribute to urban-rural differences in vaccine responses in Uganda? A causal mediation analysis using data from three linked randomised controlled trials." [Internet]. London School of Hygiene & Tropical Medicine; 2024. Available from: https://doi.org/10.17037/DATA.00003761.

Natukunda, A, Nkurunungi, G, Zirimenya, L, Nassuuna, J, Elliott, AM and Webb, E (2024). Data supporting "Does schistosome or malaria exposure contribute to urban-rural differences in vaccine responses in Uganda? A causal mediation analysis using data from three linked randomised controlled trials.". [Data Collection]. London School of Hygiene & Tropical Medicine, London, United Kingdom. https://doi.org/10.17037/DATA.00003761.

Description

This dataset comprises individual-level data from participants in the POPVAC series of three randomised controlled trials. POPVAC A was conducted among schoolchildren from Koome islands, Uganda (a schistosomiasis-endemic setting), POPVAC B was conducted among schoolchildren from Jinja district, Uganda (a malaria-endemic setting), POPVAC C was conducted among schoolchildren from Entebbe, Uganda (a lower infection prevalence setting).

Additional information

To access the data, requests must be made to the PI (Professor Alison Elliott). The request will be reviewed by the PI together with the POPVAC investigator team, in consultation with the POPVAC steering committee. The request will be reviewed based on scientific value and to ensure there is no overlap with existing work. If the request is approved, before data is shared, ethics approval will need to be obtained in your host institution and a Data Transfer Agreement with the MRC/UVRI and LSHTM Uganda Research Unit must be completed.

Methods

Data capture method

Questionnaire, Lab observation

Data Collection Period

From	To
July 2019	September 2022

Date (Date submitted to LSHTM repository)

29 January 2024

Language(s) of written materials

English

People & Groups

Data Creators	Natukunda, A, Nkurunungi, G, Zirimenya, L, Nassuuna, J, Elliott, AM and Webb, E
Associated roles	Zziwa, C (Researcher), Ninsiima, C (Researcher), Tumusiime, J (Researcher), Nyanzi, R (Researcher), Namutebi, M (Researcher), Kiwudhu, F (Researcher), van Dam, G (Researcher), Corstjens, P (Researcher), Kizindo, R (Researcher), Nkangi, R (Researcher), Kabagenyi, J (Researcher), Nassanga, B (Researcher), Cose, S (Researcher), Wajja, A (Researcher) and Kaleebu, P (Researcher)
LSHTM Faculty/Department	MRC/UVRI and LSHTM Uganda Research Unit
Participating Institutions	MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda, London School of Hygiene & Tropical Medicine, London, United Kingdom, Leiden University Medical Centre, Leiden, Netherlands, Uganda Virus Research Institute, Entebbe, Uganda