Nassuuna, J, Zirimenya, L, Nkurunungi, G, Natukunda, A, Webb, E and Elliott, AM. 2024. Data supporting: "The effect of BCG revaccination on the response to unrelated vaccines in urban Ugandan adolescents: results of the POPVAC C randomised, controlled trial". [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: https://doi.org/10.17037/DATA.00003760.
Nassuuna, J, Zirimenya, L, Nkurunungi, G, Natukunda, A, Webb, E and Elliott, AM. Data supporting: "The effect of BCG revaccination on the response to unrelated vaccines in urban Ugandan adolescents: results of the POPVAC C randomised, controlled trial" [Internet]. London School of Hygiene & Tropical Medicine; 2024. Available from: https://doi.org/10.17037/DATA.00003760.
Nassuuna, J, Zirimenya, L, Nkurunungi, G, Natukunda, A, Webb, E and Elliott, AM (2024). Data supporting: "The effect of BCG revaccination on the response to unrelated vaccines in urban Ugandan adolescents: results of the POPVAC C randomised, controlled trial". [Data Collection]. London School of Hygiene & Tropical Medicine, London, United Kingdom. https://doi.org/10.17037/DATA.00003760.
Description
This dataset comprises individual-level data from participants in the POPVAC C randomised controlled trial. POPVAC C was an open-label randomised controlled trial of Bacillus Calmette Guérin (BCG) revaccination versus no BCG among schoolchildren in Entebbe, Uganda (ISRCTN10482904). The aim of the trial was to comprehensively address the hypothesis that revaccination with BCG might enhance responses to unrelated vaccines. A portfolio of vaccines, of potential benefit to the children and comprising live, inert, oral and parenteral, was provided to enable a comprehensive assessment and comparison of effects of BCG revaccination on immune response to vaccines with different characteristics.
Additional information
To access the data, requests must be made to the PI (Professor Alison Elliott). The request will be reviewed by the PI together with the POPVAC investigator team, in consultation with the POPVAC steering committee. The request will be reviewed based on scientific value and to ensure there is no overlap with existing work. If the request is approved, before data is shared, ethics approval will need to be obtained in your host institution and a Data Transfer Agreement with the MRC/UVRI and LSHTM Uganda Research Unit must be completed.
Keywords
Data capture method | Questionnaire, Lab observation | ||||
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Data Collection Period |
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Date (Date submitted to LSHTM repository) | 29 January 2024 | ||||
Language(s) of written materials | English |
Data Creators | Nassuuna, J, Zirimenya, L, Nkurunungi, G, Natukunda, A, Webb, E and Elliott, AM |
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Associated roles | Zziwa, C (Researcher), Ninsiima, C (Researcher), Apule, B (Researcher), Onen, C (Researcher), Amongin, S (Researcher), Serubanja, J (Researcher), Tumwesigye, P (Researcher), Nsubuga, D (Researcher), Amongin, R (Researcher), Kayiwa, J (Researcher), Kabagenyi, J (Researcher), Cose, S (Researcher), Wajja, A (Researcher) and Kaleebu, P (Researcher) |
LSHTM Faculty/Department | MRC/UVRI and LSHTM Uganda Research Unit |
Participating Institutions | MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda, Uganda Virus Research Institute, Entebbe, Uganda, London School of Hygiene & Tropical Medicine, London, United Kingdom |
Funders |
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Date Deposited | 02 Feb 2024 14:24 |
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Last Modified | 02 Feb 2024 14:51 |
Publisher | London School of Hygiene & Tropical Medicine |
Downloads
Data / Code
Restricted to: Request access for all
Filename: POPVAC_C_data.txt
Description: POPVAC C data on BCG trial intervention, and vaccine responses
Licence: Data Sharing Agreement
Content type: Dataset
File size: 56B
Mime-Type: text/plain
Documentation
Filename: POPVAC_C_data_codebook.html
Description: POPVAC C data dictionary
Content type: Textual content
File size: 15kB
Mime-Type: text/html
Filename: 3760-UserGuide.html
Description: User guide for POPVAC C dataset
Content type: Textual content
File size: 7kB
Mime-Type: text/html