Data supporting: "The effect of BCG revaccination on the response to unrelated vaccines in urban Ugandan adolescents: results of the POPVAC C randomised, controlled trial" – User Guide

Persistent identifier

10.17037/DATA.00003760

Description

This dataset comprises individual-level data from participants in the POPVAC C randomised controlled trial. POPVAC C was an open-label randomised controlled trial of Bacillus Calmette Guérin (BCG) revaccination versus no BCG among schoolchildren in Entebbe, Uganda (ISRCTN10482904). The aim of the trial was to comprehensively address the hypothesis that revaccination with BCG might enhance responses to unrelated vaccines. A portfolio of vaccines, of potential benefit to the children and comprising live, inert, oral and parenteral, was provided to enable a comprehensive assessment and comparison of effects of BCG revaccination on immune response to vaccines with different characteristics.

Data collection methods

Collection procedures are outlined in "The effect of BCG revaccination on the response to unrelated vaccines in urban Ugandan adolescents: results of the POPVAC C randomised, controlled trial".

Geographic regions

Entebbe, Uganda.

Key dates

Population

Entebbe, Uganda

Ethics

Organisation Ethics ID Other information
MRC/UVRI and LSHTM Uganda Research Unit 16034 POPVAC C randomised controlled trial

Keywords

BCG revaccination, Vaccine response, Children

Language of written material

English

Project information

Project name Funder/sponsor Grant number
POPVAC C randomised controlled trial Medical Research Council MR/R02118X/1 and MC_PC_21034

Creators

Forename Surname Faculty / Dept Institution Role
Jacent Nassuuna   MRC/UVRI and LSHTM Uganda Research Unit Data Creator
Ludoviko Zirimenya Faculty of Infectious and Tropical Diseases / Department of Clinical Research London School of Hygiene & Tropical Medicine Data Creator
Gyaviira Nkurunungi   MRC/UVRI and LSHTM Uganda Research Unit Data Creator
Agnes Natukunda Faculty of Epidemiology and Population Health / Department of Infectious Disease Epidemiology and International Health London School of Hygiene & Tropical Medicine Data Creator
Emily Webb Faculty of Infectious and Tropical Diseases / Department of Clinical Research London School of Hygiene & Tropical Medicine Data Creator
Alison M. Elliott Faculty of Epidemiology and Population Health / Department of Infectious Disease Epidemiology and International Health London School of Hygiene & Tropical Medicine Data Creator

Associated roles

Forename Surname Faculty / Dept Institution Role
Christopher Zziwa   MRC/UVRI and LSHTM Uganda Research Unit Researcher
Caroline Ninsiima   MRC/UVRI and LSHTM Uganda Research Unit Researcher
Barbara Apule   MRC/UVRI and LSHTM Uganda Research Unit Researcher
Caroline Onen   MRC/UVRI and LSHTM Uganda Research Unit Researcher
Suzan Amongin     Researcher
Joel Serubanja   MRC/UVRI and LSHTM Uganda Research Unit Researcher
Pius Tumwesigye     Researcher
Denis Nsubuga   MRC/UVRI and LSHTM Uganda Research Unit Researcher
Rebecca Amongin     Researcher
John Kayiwa   MRC/UVRI and LSHTM Uganda Research Unit Researcher
Joyce Kabagenyi     Researcher
Stephen Cose   MRC/UVRI and LSHTM Uganda Research Unit Researcher
Anne Wajja   MRC/UVRI and LSHTM Uganda Research Unit Researcher
Pontiano Kaleebu   MRC/UVRI and LSHTM Uganda Research Unit Researcher

File description

Filename Description Access status Licence
POPVAC_C_data POPVAC C data on BCG trial intervention, and vaccine responses Controlled – request access Data sharing agreement
POPVAC_C_data_codebook POPVAC C data dictionary Open access Creative Commons Attribution (CCBY)
3760-UserGuide User guide for POPVAC C dataset Open access Creative Commons Attribution (CCBY)