Genome-wide association studies identify 137 loci for DNA methylation biomarkers of aging
McCartney, D, Min, J, Richmond, R, Lu, A, Sobczyk, M, Davies, G, Broer, L, Guo, X, Jeong, A, Jung, J, Kasela, S, Katrinli, S, Kuo, P, Matias-Garcia, P, Mishra, P, Nygaard, M, Palviainen, T, Patki, A, Raffield, L, Ratliff, S, Richardson, T, Robinson, O, Sorensen, M, Sun, D, Tsai, P, van der Zee, M, Wang, X, Wang, Y, Xia, R, Xu, Z, Yao, J, Zhao, W, Deary, I, Relton, CL, Horvath, S and Marioni, R.
2020.
Genome-wide association studies identify 137 loci for DNA methylation biomarkers of aging.
[Online].
University of Edinburgh, Edinburgh, Scotland.
Available from:
McCartney, D, Min, J, Richmond, R, Lu, A, Sobczyk, M, Davies, G, Broer, L, Guo, X, Jeong, A, Jung, J, Kasela, S, Katrinli, S, Kuo, P, Matias-Garcia, P, Mishra, P, Nygaard, M, Palviainen, T, Patki, A, Raffield, L, Ratliff, S, Richardson, T, Robinson, O, Sorensen, M, Sun, D, Tsai, P, van der Zee, M, Wang, X, Wang, Y, Xia, R, Xu, Z, Yao, J, Zhao, W, Deary, I, Relton, CL, Horvath, S and Marioni, R.
Genome-wide association studies identify 137 loci for DNA methylation biomarkers of aging
[Internet].
University of Edinburgh;
2020.
Available from:
McCartney, D, Min, J, Richmond, R, Lu, A, Sobczyk, M, Davies, G, Broer, L, Guo, X, Jeong, A, Jung, J, Kasela, S, Katrinli, S, Kuo, P, Matias-Garcia, P, Mishra, P, Nygaard, M, Palviainen, T, Patki, A, Raffield, L, Ratliff, S, Richardson, T, Robinson, O, Sorensen, M, Sun, D, Tsai, P, van der Zee, M, Wang, X, Wang, Y, Xia, R, Xu, Z, Yao, J, Zhao, W, Deary, I, Relton, CL, Horvath, S and Marioni, R
(2020).
Genome-wide association studies identify 137 loci for DNA methylation biomarkers of aging.
[Data Collection].
University of Edinburgh, Edinburgh, Scotland.
Description
These files contain summary statistics for meta-analysis GWAS of six traits in European, African and Trans-Ancestry. There are 18 files in total - 6 for each ancestry by 3 for each trait. The traits are DNA methylation proxies for granulocyte proportions (gran) and plasminogen activator inhibitor-1 (PAI1), and four epigenetic age acceleration measures of: PhenoAge, GrimAge, HannumAge, and Intrinsic Epigenetic Age Acceleration (IEAA).
McCartney, D, Min, J, Richmond, R, Lu, A, Sobczyk, M, Davies, G, Broer, L, Guo, X, Jeong, A, Jung, J, Kasela, S, Katrinli, S, Kuo, P, Matias-Garcia, P, Mishra, P, Nygaard, M, Palviainen, T, Patki, A, Raffield, L, Ratliff, S, Richardson, T, Robinson, O, Sorensen, M, Sun, D, Tsai, P, van der Zee, M, Wang, X, Wang, Y, Xia, R, Xu, Z, Yao, J, Zhao, W, Deary, I, Relton, CL, Horvath, S and Marioni, R
