Genome-wide association studies identify 137 loci for DNA methylation biomarkers of aging
McCartney, D, Min, J, Richmond, R, Lu, A, Sobczyk, M, Davies, G, Broer, L, Guo, X, Jeong, A, Jung, J, Kasela, S, Katrinli, S, Kuo, P, Matias-Garcia, P, Mishra, P, Nygaard, M, Palviainen, T, Patki, A, Raffield, L, Ratliff, S, Richardson, T, Robinson, O, Sorensen, M, Sun, D, Tsai, P, van der Zee, M, Wang, X, Wang, Y, Xia, R, Xu, Z, Yao, J, Zhao, W, Deary, I, Relton, CL
, Horvath, S and Marioni, R
(2020).
Genome-wide association studies identify 137 loci for DNA methylation biomarkers of aging.
[Dataset].
University of Edinburgh, Edinburgh, Scotland.
, Horvath, S and Marioni, R
(2020).
Genome-wide association studies identify 137 loci for DNA methylation biomarkers of aging.
[Dataset].
University of Edinburgh, Edinburgh, Scotland.
These files contain summary statistics for meta-analysis GWAS of six traits in European, African and Trans-Ancestry. There are 18 files in total - 6 for each ancestry by 3 for each trait. The traits are DNA methylation proxies for granulocyte proportions (gran) and plasminogen activator inhibitor-1 (PAI1), and four epigenetic age acceleration measures of: PhenoAge, GrimAge, HannumAge, and Intrinsic Epigenetic Age Acceleration (IEAA).
Keywords
ageing, GWAS, Epigenetics, DNA Methylation| Item Type | Dataset |
|---|---|
| Capture method | Experiment |
| Date | 1 July 2020 |
| Language(s) of written materials | English |
| Creator(s) |
McCartney, D, Min, J, Richmond, R, Lu, A, Sobczyk, M, Davies, G, Broer, L, Guo, X, Jeong, A, Jung, J, Kasela, S, Katrinli, S, Kuo, P, Matias-Garcia, P, Mishra, P, Nygaard, M, Palviainen, T, Patki, A, Raffield, L, Ratliff, S, Richardson, T, Robinson, O, Sorensen, M, Sun, D, Tsai, P, van der Zee, M, Wang, X, Wang, Y, Xia, R, Xu, Z, Yao, J, Zhao, W, Deary, I, Relton, CL, Horvath, S and Marioni, R
|
| LSHTM Faculty/Department | Academic Services & Administration > Directorate |
| Participating Institutions | Study consortium |
| Funders |
Project Funder Grant Number Funder URI |
| Date Deposited | 26 May 2023 09:09 |
| Last Modified | 08 Jun 2023 13:14 |
| Publisher | University of Edinburgh |
No files available. Please consult associated links.
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