Genome-wide association studies identify 137 loci for DNA methylation biomarkers of aging
McCartney, D; Min, J; Richmond, R; Lu, A; Sobczyk, M; Davies, G; Broer, L; Guo, X; Jeong, A; Jung, J; Kasela, S; Katrinli, S; Kuo, P; Matias-Garcia, P; Mishra, P; Nygaard, M; Palviainen, T; Patki, A; Raffield, L; Ratliff, S; Richardson, T; Robinson, O; Sorensen, M; Sun, D; Tsai, P; van der Zee, M; Wang, X; Wang, Y; Xia, R; Xu, Z; Yao, J; Zhao, W; Deary, I; Relton, CL
; Horvath, S and Marioni, R
(2020).
Genome-wide association studies identify 137 loci for DNA methylation biomarkers of aging.
[Dataset].
University of Edinburgh, Edinburgh, Scotland.
; Horvath, S and Marioni, R
(2020).
Genome-wide association studies identify 137 loci for DNA methylation biomarkers of aging.
[Dataset].
University of Edinburgh, Edinburgh, Scotland.
These files contain summary statistics for meta-analysis GWAS of six traits in European, African and Trans-Ancestry. There are 18 files in total - 6 for each ancestry by 3 for each trait. The traits are DNA methylation proxies for granulocyte proportions (gran) and plasminogen activator inhibitor-1 (PAI1), and four epigenetic age acceleration measures of: PhenoAge, GrimAge, HannumAge, and Intrinsic Epigenetic Age Acceleration (IEAA).
Keywords
ageing; GWAS; Epigenetics; DNA Methylation| Item Type | Dataset |
|---|---|
| Resource Type |
Resource Type Resource Description Dataset Quantitative |
| Capture method | Experiment |
| Date | 1 July 2020 |
| Language(s) of written materials | English |
| Creator(s) |
McCartney, D; Min, J; Richmond, R; Lu, A; Sobczyk, M; Davies, G; Broer, L; Guo, X; Jeong, A; Jung, J; Kasela, S; Katrinli, S; Kuo, P; Matias-Garcia, P; Mishra, P; Nygaard, M; Palviainen, T; Patki, A; Raffield, L; Ratliff, S; Richardson, T; Robinson, O; Sorensen, M; Sun, D; Tsai, P; van der Zee, M; Wang, X; Wang, Y; Xia, R; Xu, Z; Yao, J; Zhao, W; Deary, I; Relton, CL; Horvath, S and Marioni, R
|
| LSHTM Faculty/Department | Academic Services & Administration > Directorate |
| Participating Institutions | Study consortium |
| Funders |
Project Funder Grant Number Funder URI |
| Date Deposited | 26 May 2023 09:09 |
| Last Modified | 08 Jun 2023 13:14 |
| Publisher | University of Edinburgh |
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