Dataset for: Defining seropositivity thresholds for use in trachoma elimination studies

Migchelsen, S. 2016. Dataset for: Defining seropositivity thresholds for use in trachoma elimination studies. [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: https://doi.org/10.17037/DATA.111.

Migchelsen, S. Dataset for: Defining seropositivity thresholds for use in trachoma elimination studies [Internet]. London School of Hygiene & Tropical Medicine; 2016. Available from: https://doi.org/10.17037/DATA.111.

Migchelsen, S (2016). Dataset for: Defining seropositivity thresholds for use in trachoma elimination studies. [Data Collection]. London School of Hygiene & Tropical Medicine, London, United Kingdom. https://doi.org/10.17037/DATA.111.

Description

Data sets from 2700 Uganda, 952 Laotian and 1868 Gambian participants who have informed consent to participate in a cluster-randomised serological study to determine the seroprevalence of antibodies against Chlamydia trachomatis. Specimens were analysed from May 2014-May 2016. Each data set contains normalised OD values for an anti-Pgp3 specific ELISA, which were used to generate a series of thresholds to define seropositive and seronegative samples.

Methods

Description of data capture

Dried blood spots were collected onto filter paper from a finger-prick blood sample from consenting participants in Laos, Uganda and The Gambia. Samples were allowed to air-dry, then were stored at -20C before being shipped to LSHTM for testing. Samples were eluted overnight and assayed using an-Pgp3 specific ELISA. Data presented are normalised OD values (read at optical density 450)

Data capture method

Experiment: Laboratory

Data Collection Period

From	To
February 2014	November 2014

Date (Date submitted to LSHTM repository)

August 2016

Geographical area covered (offline during plugin upgrade)

North Latitude	East Longitude	South Latitude	West Longitude
13.8073	-13.7315	13.1636	-15.2779
3.43366	34.368	1.86434	32.775
22.6232	107.743	14.1675	101.415

Language(s) of written materials

English

People & Groups

Data Creators	Migchelsen, S
Associated roles	Mabey, D (Supervisor) and Roberts, C (Supervisor)
LSHTM Faculty/Department	Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Participating Institutions	London School of Hygiene & Tropical Medicine