Effectiveness of electronic reminders to improve medication adherence in tuberculosis patients: a cluster-randomised trial

Fielding, K, Lewis, J and Jiang, S. 2013. Effectiveness of electronic reminders to improve medication adherence in tuberculosis patients: a cluster-randomised trial. [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: https://doi.org/10.17037/DATA.4.

Fielding, K, Lewis, J and Jiang, S. Effectiveness of electronic reminders to improve medication adherence in tuberculosis patients: a cluster-randomised trial [Internet]. London School of Hygiene & Tropical Medicine; 2013. Available from: https://doi.org/10.17037/DATA.4.

Fielding, K, Lewis, J and Jiang, S (2013). Effectiveness of electronic reminders to improve medication adherence in tuberculosis patients: a cluster-randomised trial. [Data Collection]. London School of Hygiene & Tropical Medicine, London, United Kingdom. https://doi.org/10.17037/DATA.4.

Description

An anonymised dataset of 4,292 TB patients who gave informed consent to participate in a pragmatic, cluster-randomised trial of 36 districts/counties (clusters) within the provinces of Heilongjiang, Jiangsu, Hunan, and Chongqing, China between June 2011- March 2012. Dataset contains variables on stratified randomisation and cluster code, socio-demographic information, TB treatment outcomes, adherence outcomes, medication monitor problems, mobile phone problems, and the type of patient treatment management therapy initiated (if at all).

Methods

Description of data capture

A pragmatic, cluster-randomised trial of 36 districts/counties (clusters) within the provinces of Heilongjiang, Jiangsu, Hunan, and Chongqing, China. Clusters were randomised to one of four case-management approaches using stratification and restriction. The four arms were standard of care (control), or receiving adherence reminders from (i) text messages, (ii) an electronic medication monitor or (iii) both. See paper for more details on the intervention definitions. TB patients in these clusters were recruited at the start of treatment and followed up for six months. The primary outcome was the percentage of patient-months on TB treatment where at least 20% of doses were missed as measured by pill count and failure to open the medication monitor. Secondary outcomes included additional adherence measures and standard treatment outcome measures. Interventions were not masked to study staff and patients.

Data capture method

Interview: Face-to-face, Questionnaire: Fixed form - Paper, Other

Data Collection Period

From	To
1 June 2011	30 September 2012

Date (Completed)

22 August 2013

Geographical area covered

North Latitude	East Longitude	South Latitude	West Longitude
41.0992	121.729	24.99	85.8691

Language(s) of written materials

English

People & Groups

Data Creators	Fielding, K, Lewis, J and Jiang, S
Associated roles	Liu, X (Co-Investigator)
LSHTM Faculty/Department	Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology (-2023)
Research Centre	TB Centre
Research Group	MRC Tropical Epidemiology Group
Participating Institutions	National Center for TB Control and Prevention, China Center for Disease Control, Beijing, China, London School of Hygiene & Tropical Medicine, London, United Kingdom, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu, China, Chongqing Provincial TB dispensary, Chongqing, China, Heilongjiang Provincial TB dispensary, Harbin, Heilongjiang, China, Hunan Provincial TB dispensary, Changsha, Hunan, China, China-Gates Foundation TB Project National Program Management Office, China CDC, Beijing, China, Dafeng County Center for Disease Control and Prevention in Jiangsu province, Dafeng, Jiangsu, China, The Bill & Melinda Gates Foundation Beijing Office, Beijing, China

Projects

Funders

Project	Funder	Grant Number	Funder URI
Use of Innovative Tools and Delivery Approaches to Improve TB Control in China: Corn munity Randomized Trial of Mobile Text Messaging and Medication Monitor Adherence Measures	Bill and Melinda Gates Foundation	51914 & 17412	http://dx.doi.org/10.13039/100000865