Effectiveness of electronic reminders to improve medication adherence in tuberculosis patients: a cluster-randomised trial

Fielding, K

; Lewis, J and Jiang, S (2013). Effectiveness of electronic reminders to improve medication adherence in tuberculosis patients: a cluster-randomised trial. [Dataset]. London School of Hygiene & Tropical Medicine, London, United Kingdom. 10.17037/DATA.4.

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An anonymised dataset of 4,292 TB patients who gave informed consent to participate in a pragmatic, cluster-randomised trial of 36 districts/counties (clusters) within the provinces of Heilongjiang, Jiangsu, Hunan, and Chongqing, China between June 2011- March 2012. Dataset contains variables on stratified randomisation and cluster code, socio-demographic information, TB treatment outcomes, adherence outcomes, medication monitor problems, mobile phone problems, and the type of patient treatment management therapy initiated (if at all).

Keywords

tuberculosis treatment; electronic reminders; China; Adherence

Item Type	Dataset
Resource Type	Resource Type Resource Description Dataset Quantitative
Description of data capture	A pragmatic, cluster-randomised trial of 36 districts/counties (clusters) within the provinces of Heilongjiang, Jiangsu, Hunan, and Chongqing, China. Clusters were randomised to one of four case-management approaches using stratification and restriction. The four arms were standard of care (control), or receiving adherence reminders from (i) text messages, (ii) an electronic medication monitor or (iii) both. See paper for more details on the intervention definitions. TB patients in these clusters were recruited at the start of treatment and followed up for six months. The primary outcome was the percentage of patient-months on TB treatment where at least 20% of doses were missed as measured by pill count and failure to open the medication monitor. Secondary outcomes included additional adherence measures and standard treatment outcome measures. Interventions were not masked to study staff and patients.
Capture method	Interview: Face-to-face, Questionnaire: Fixed form - Paper, Other
Collection Period	From To 1 June 2011 30 September 2012
Date	22 August 2013
Geographical area covered (offline during plugin upgrade)	North East South West 41.0992 121.729 24.99 85.8691
Language(s) of written materials	English
Creator(s)	Fielding, K ; Lewis, J and Jiang, S
Associated roles	Liu, X (Co-Investigator)
LSHTM Faculty/Department	Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology (-2023)
Research Centre	TB Centre
Research Group	MRC Tropical Epidemiology Group
Participating Institutions	National Center for TB Control and Prevention, China Center for Disease Control, Beijing, China; London School of Hygiene & Tropical Medicine, London, United Kingdom; Jiangsu Provincial Center for Disease Control and Prevention, Nanjing, Jiangsu, China; Chongqing Provincial TB dispensary, Chongqing, China; Heilongjiang Provincial TB dispensary, Harbin, Heilongjiang, China; Hunan Provincial TB dispensary, Changsha, Hunan, China; China-Gates Foundation TB Project National Program Management Office, China CDC, Beijing, China; Dafeng County Center for Disease Control and Prevention in Jiangsu province, Dafeng, Jiangsu, China; The Bill & Melinda Gates Foundation Beijing Office, Beijing, China
Funders	Project Funder Grant Number Funder URI Use of Innovative Tools and Delivery Approaches to Improve TB Control in China: Corn munity Randomized Trial of Mobile Text Messaging and Medication Monitor Adherence Measures Bill and Melinda Gates Foundation 51914 & 17412 http://dx.doi.org/10.13039/100000865
Date Deposited	02 Jul 2015 17:09
Last Modified	26 Nov 2025 13:41
Publisher	London School of Hygiene & Tropical Medicine

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Data / Code

ChinaCRT_dataset.csv

subject: Data
: Available under Creative Commons: Attribution-Noncommercial-Share Alike 3.0
info: An anonymised dataset of 4,292 TB patients who gave informed consent to participate in a pragmatic, cluster-randomised trial. Each row represents a study participant
description: text/plain
folder_info: 766kB