Data collected during weekly surveys during the rainy season, when blood samples were taken for determination of malaria infection. Data was collected as part of the AZ-SMC trial (clinicaltrials.gov NCT02211729) in Houndé District, Burkina Faso and Bougouni District, Mali between 2014 and 2016.
Additional information
This dataset is restricted for ethical reasons related to the original study. Access will be provided for use in ethically-approved research on condition that a Data Transfer Agreement is signed. This will set out conditions on permitted use to ensure participant confidentiality is maintained at all times.
Data on morbidity events (including the primary outcome) were captured through a passive surveillance system at health centres and hospitals in the study area. Data on administration of study drugs was captured using Tablet PCs at the time that children were contacted to provide the monthly SMC treatments. Data on the prevalence of P falciparum infection were collected from study children at cross-sectional surveys at the end of each malaria transmission season, at weekly surveys conducted in a sample of study children, and from school-age children resident in the study area at the end of each rainy season. The treatment efficacy of sulphadoxine-pyrimethamine plus amodiaquine was assessed in children with asymptomatic P falciparum infections at the end of the study in December 2016.
London School of Hygiene & Tropical Medicine, London, United Kingdom, Malaria Research and Training Center, University of Bamako, Bamako, Mali, Ministry of Health, Ouagadougou, Burkina Faso, Research Institute of Health Sciences (IRSS), Ouagadougou, Burkina Faso
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