A seroepidemiological study of serogroup A meningococcal infection in the African meningitis belt
Manigart, O, Trotter, C, Findlow, H, Assefa, A, Mihret, W, Demisse, TM, Yeshitela, B, Osei, I, Hodgson, A, Quaye, SL, Sow, S, Coulibaly, M, Diallo, K, Traore, A, Collard, J, Boukary, R, Djermakoye, O, Mahamane, AE, Jusot, J, Sokhna, C, Alavo, S, Doucoure, S, Ba, EH, Dieng, M, Diallo, A, Daugla, DM, Omotara, B, Chandramohan, D
, Hassan-King, M, Nascimento, M, Woukeu, A, Borrow, R, Stuart, J and Greenwood, B
(2016).
A seroepidemiological study of serogroup A meningococcal infection in the African meningitis belt.
[Dataset].
London School of Hygiene & Tropical Medicine, London, United Kingdom.
10.17037/DATA.34.
, Hassan-King, M, Nascimento, M, Woukeu, A, Borrow, R, Stuart, J and Greenwood, B
(2016).
A seroepidemiological study of serogroup A meningococcal infection in the African meningitis belt.
[Dataset].
London School of Hygiene & Tropical Medicine, London, United Kingdom.
10.17037/DATA.34.
The dataset contains results of a cross-sectional survey of meningococcal carriage and immunity performed in several countries of the African meningitis belt in 2010. A standardised enzyme-linked immunosorbent assay (ELISA) for measuring meningococcal serogroup A IgG antibodies was used to measure antibody concentrations in 3930 individuals. Anonymised information on the age, sex, residence, carriage status and other risk factors is included.
Additional Information
HTML copy of codebook and user guide added to record on 28 Jan 2025 (previously PDF). Consult codebook for variable list and access conditions.
Keywords
Meningitis, Neisseria meningitidis, ELISA, Antibody, Seroprevalence| Item Type | Dataset |
|---|---|
| Description of data capture | Cross-sectional meningococcal carriage surveys were conducted in seven countries across the meningitis belt between July 1st 2010 and December 31st 2010. Subjects were selected randomly from within populations which were part of a routine demographic survey system (DHSS) or in which a census had recently been performed. The study population was recruited from urban and rural populations and stratified into four age groups: < 5 years, 5-14 years, 15-29 years and 30 years or older. A short questionnaire collecting demographic details and information on potential risk factors was completed for each participant and each household recruited. Blood samples were collected from the first 100 subjects surveyed within each of the four age bands in both urban and rural study sites, giving an overall target of 800 samples per country. This target was achieved, except in Senegal where there was some resistance to the collection of blood samples. A 5 mL sample was collected, serum separated within six hours of collection and then stored at -20°C until assayed. |
| Capture method | Questionnaire |
| Collection Period |
From To 1 July 2010 31 December 2010 |
| Date | 21 January 2016 |
| Geographical area covered (offline during plugin upgrade) |
North Latitude East Longitude South Latitude West Longitude 13.7661 45.1318 4.49155 34.8486 21.384 15.4248 13.0822 5.22949 18.4926 3.12012 13.8514 -16.3916 13.1677 14.0186 5.62965 3.73535 |
| Language(s) of written materials | English |
| Creator(s) |
Manigart, O, Trotter, C, Findlow, H, Assefa, A, Mihret, W, Demisse, TM, Yeshitela, B, Osei, I, Hodgson, A, Quaye, SL, Sow, S, Coulibaly, M, Diallo, K, Traore, A, Collard, J, Boukary, R, Djermakoye, O, Mahamane, AE, Jusot, J, Sokhna, C, Alavo, S, Doucoure, S, Ba, EH, Dieng, M, Diallo, A, Daugla, DM, Omotara, B, Chandramohan, D, Hassan-King, M, Nascimento, M, Woukeu, A, Borrow, R, Stuart, J and Greenwood, B
|
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Disease Control |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom, University of Cambridge, Cambridge, United Kingdom, Public Health England, Armauer Hansen Research Institute, Navrongo Health Research Centre, Navrongo, Ghana, Centre pour les Vaccins en Développement, Centre de Recherche Médicale et Sanitaire, Institut de Recherche pour le Développement, Centre de Support en Santé International, University of Maiduguri, Maiduguri, Nigeria |
| Funders |
Project Funder Grant Number Funder URI The African Meningococcal Carriage Consortium (MenAfriCar) 086546 http://dx.doi.org/10.13039/100010269 The African Meningococcal Carriage Consortium (MenAfriCar) OPP51251 http://dx.doi.org/10.13039/100000865 |
| Date Deposited | 27 Jan 2016 12:52 |
| Last Modified | 28 Jan 2025 10:38 |
| Publisher | London School of Hygiene & Tropical Medicine |
MenAfriCar_ELISA.csv
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subject - Data
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lock - Restricted to Request access for all
- Data Sharing Agreement
- Available under Data Sharing Agreement
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info - Anonymised dataset containing variables on meningococcal carriage status, strain details, commensal Neisseria carriage status, recent vaccination history, serogroup A specific IgG ELISA antibody concentration, and other details.
description - text/plain
- folder_info
- 64B
MenAfriCar_ELISA_codebook.html
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subject - Documentation
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- Available under Creative Commons: Attribution 4.0
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info - MenAfriCar ELISA codebook
html - text/html
- folder_info
- 6kB
Adult_Questionnaire.pdf
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subject - Study Instrument
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Adult Short Individual Questionnaire (ASIQ)
picture_as_pdf - application/pdf
- folder_info
- 22kB
Children_Questionnaire.pdf
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subject - Study Instrument
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Children Short Individual Questionnaire (CSIQ)
picture_as_pdf - application/pdf
- folder_info
- 23kB
Household_Questionnaire.pdf
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subject - Study Instrument
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Short Household Questionnaire (SHQ)
picture_as_pdf - application/pdf
- folder_info
- 23kB
ConsentFormAdults.pdf
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subject - Documentation
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Consent form for adults
picture_as_pdf - application/pdf
- folder_info
- 199kB
0034_UserGuide.html
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subject - Documentation
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- Available under Creative Commons: Attribution 4.0
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info - MenAfriCar ELISA user guide
html - text/html
- folder_info
- 16kB
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