A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia
James, P
, Jawla, O, Mohammed, N, Ceesay, K, Akemokwe, F, Sonko, B, Sise, E, Prentice, A and Silver, M
(2019).
A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia.
[Dataset].
PLOS Medicine.
, Jawla, O, Mohammed, N, Ceesay, K, Akemokwe, F, Sonko, B, Sise, E, Prentice, A and Silver, M
(2019).
A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia.
[Dataset].
PLOS Medicine.
Infant DNA methylation profiles are associated with their mother’s periconceptional nutritional status. DNA methylation relies on nutritional inputs for one-carbon metabolic pathways, including the efficient recycling of homocysteine. This randomised controlled trial in nonpregnant women in rural Gambia tests the efficacy of a novel nutritional supplement designed to improve one-carbon-related nutrient status by reducing plasma homocysteine, and assesses its potential future use in preconception trials.
Keywords
plasma homocysteine, DNA methylation profiles, nonpregnant women, measure plasma homocysteine| Item Type | Dataset |
|---|---|
| Capture method | Experiment |
| Date | 13 August 2019 |
| Language(s) of written materials | English |
| Creator(s) |
James, P, Jawla, O, Mohammed, N, Ceesay, K, Akemokwe, F, Sonko, B, Sise, E, Prentice, A and Silver, M
|
| LSHTM Faculty/Department | MRC Unit The Gambia at LSHTM |
| Participating Institutions | London School of Hygiene & Tropical Medicine |
| Date Deposited | 22 Aug 2019 15:27 |
| Last Modified | 08 Jul 2021 12:52 |
| Publisher | PLOS Medicine |
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