In-depth proteomic characterization of Schistosoma haematobium: Towards the development of new tools for elimination
Sotillo, J; Pearson, MS; Becker, L; Mekonnen, GG; Amoah, AS
; Dam, Gv; Corstjens, PL; Murray, J; Mduluza, T; Mutapi, F and Loukas, A
(2019).
In-depth proteomic characterization of Schistosoma haematobium: Towards the development of new tools for elimination.
[Dataset].
PLoS Neglected Tropical Diseases.
https://doi.org/10.1371/journal.pntd.0007362.s001
; Dam, Gv; Corstjens, PL; Murray, J; Mduluza, T; Mutapi, F and Loukas, A
(2019).
In-depth proteomic characterization of Schistosoma haematobium: Towards the development of new tools for elimination.
[Dataset].
PLoS Neglected Tropical Diseases.
https://doi.org/10.1371/journal.pntd.0007362.s001
Schistosomiasis is a neglected disease affecting hundreds of millions worldwide. Of the three main species affecting humans, Schistosoma haematobium is the most common, and is the leading cause of urogenital schistosomiasis. S. haematobium infection can cause different urogenital clinical complications, particularly in the bladder, and furthermore, this parasite has been strongly linked with squamous cell carcinoma. A comprehensive analysis of the molecular composition of its different proteomes will contribute to developing new tools against this devastating disease.
Keywords
In-depth proteomic characterization; tegument extracts; egg proteomes; OFFGEL; protein fractionation approach; infection; elimination Background Schistosomiasis; Schistosoma haematobium; high-throughput mass spectrometry| Item Type | Dataset |
|---|---|
| Resource Type |
Resource Type Resource Description Dataset Quantitative |
| Capture method | Experiment |
| Date | 15 May 2019 |
| Language(s) of written materials | English |
| Creator(s) |
Sotillo, J; Pearson, MS; Becker, L; Mekonnen, GG; Amoah, AS; Dam, Gv; Corstjens, PL; Murray, J; Mduluza, T; Mutapi, F and Loukas, A
|
| LSHTM Faculty/Department | Faculty of Epidemiology and Population Health > Dept of Population Health (2012- ) |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Funders |
Project Funder Grant Number Funder URI UNSPECIFIED 1037304 http://dx.doi.org/10.13039/501100000925 |
| Date Deposited | 18 Jul 2019 14:57 |
| Last Modified | 17 Feb 2026 16:11 |
| Publisher | PLoS Neglected Tropical Diseases |
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