Comparative genomic analyses of Trypanosoma cruzi experimental hybrids
Matos, GM, Lewis, MD
, Talavera-López, C, Yeo, M, Grisard, EC, Messenger, LA, Miles, MA and Andersson, B
(2021).
Comparative genomic analyses of Trypanosoma cruzi experimental hybrids.
[Dataset].
NCBI BioProject.
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA748998
, Talavera-López, C, Yeo, M, Grisard, EC, Messenger, LA, Miles, MA and Andersson, B
(2021).
Comparative genomic analyses of Trypanosoma cruzi experimental hybrids.
[Dataset].
NCBI BioProject.
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA748998
To investigate the effects of clonal reproduction and genetic exchange on the T. cruzi genome we selected two closely related TcI strains (P1, P2) and three hybrid clones that were generated from a P1 x P2 cross (1C2, 1D12, 2C1) (Gaunt et al. 2003). We have used whole genome sequencing to characterize both the parental and hybrid strains, as well as three clone isolates of each parental and hybrid strain after 800 generations of growth in vitro.
Additional Information
The dataset author list is described in the 'Data Availability' section of 10.7554/eLife.75237.
Keywords
Genetics and Genomics, Microbiology and Infectious Disease, Trypanosoma cruzi, Genetic exchange, Comparative genomics, Microevolution| Item Type | Dataset |
|---|---|
| Capture method | Experiment |
| Date | 22 July 2021 |
| Language(s) of written materials | English |
| Creator(s) |
Matos, GM, Lewis, MD, Talavera-López, C, Yeo, M, Grisard, EC, Messenger, LA, Miles, MA and Andersson, B
|
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Department of Infection Biology |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Date Deposited | 28 Jun 2022 15:42 |
| Last Modified | 28 Jun 2022 15:42 |
| Publisher | NCBI BioProject |
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