Dataset for: Defining seropositivity thresholds for use in trachoma elimination studies
Migchelsen, S
(2016).
Dataset for: Defining seropositivity thresholds for use in trachoma elimination studies.
[Data Collection].
London School of Hygiene & Tropical Medicine, London, United Kingdom.
10.17037/DATA.111.
(2016).
Dataset for: Defining seropositivity thresholds for use in trachoma elimination studies.
[Data Collection].
London School of Hygiene & Tropical Medicine, London, United Kingdom.
10.17037/DATA.111.
Data sets from 2700 Uganda, 952 Laotian and 1868 Gambian participants who have informed consent to participate in a cluster-randomised serological study to determine the seroprevalence of antibodies against Chlamydia trachomatis. Specimens were analysed from May 2014-May 2016.
Each data set contains normalised OD values for an anti-Pgp3 specific ELISA, which were used to generate a series of thresholds to define seropositive and seronegative samples.
Keywords
trachoma, serology, serosurveillance, seroepidimiology| Item Type | Data Collection |
|---|---|
| Description of data capture | Dried blood spots were collected onto filter paper from a finger-prick blood sample from consenting participants in Laos, Uganda and The Gambia. Samples were allowed to air-dry, then were stored at -20C before being shipped to LSHTM for testing. Samples were eluted overnight and assayed using an-Pgp3 specific ELISA. Data presented are normalised OD values (read at optical density 450) |
| Capture method | Experiment: Laboratory |
| Collection Period |
From To February 2014 November 2014 |
| Date | August 2016 |
| Geographical area covered (offline during plugin upgrade) |
North Latitude East Longitude South Latitude West Longitude 13.8073 -13.7315 13.1636 -15.2779 3.43366 34.368 1.86434 32.775 22.6232 107.743 14.1675 101.415 |
| Language(s) of written materials | English |
| Creator(s) |
Migchelsen, S
|
| Associated roles | Mabey, D (Supervisor) and Roberts, C (Supervisor) |
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Clinical Research |
| Participating Institutions | London School of Hygiene & Tropical Medicine |
| Funders |
Project Funder Grant Number Funder URI |
| Date Deposited | 02 Sep 2016 16:00 |
| Last Modified | 27 Jan 2025 15:26 |
| Publisher | London School of Hygiene & Tropical Medicine |
UserGuide.pdf
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subject - Documentation
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - User guide for Optical Density dataset
picture_as_pdf - application/pdf
- folder_info
- 373kB
Data_dictionary.txt
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subject - Documentation
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Data dictionary for Gambia, Uganda, and Laos datasets
description - text/plain
- folder_info
- 766B
InformationSheet_Adult.pdf
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subject - Documentation
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Information sheet and consent form distributed to adult participants
picture_as_pdf - application/pdf
- folder_info
- 234kB
InformationSheet_Child.pdf
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subject - Documentation
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Information sheet and consent form distributed to child participants
picture_as_pdf - application/pdf
- folder_info
- 237kB
Gambia_normalisedOD.txt
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subject - Data
- Data: Open Data Commons Attribution License (Attribution)
- Available under Open Data Commons Attribution License (Attribution)
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info - Normalised Optical Density values and thresholds-Gambian specimens. Exported on 17 August 2016.
description - text/plain
- folder_info
- 65kB
Uganda_normalisedOD.txt
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subject - Data
- Data: Open Data Commons Attribution License (Attribution)
- Available under Open Data Commons Attribution License (Attribution)
-
info - Normalised Optical Density values and thresholds-Ugandan specimens. Exported on 17 August 2016.
description - text/plain
- folder_info
- 79kB
Laos_normalisedOD.txt
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subject - Data
- Data: Open Data Commons Attribution License (Attribution)
- Available under Open Data Commons Attribution License (Attribution)
-
info - Normalised Optical Density values and thresholds-Laotian specimens. Exported on 17 August 2016.
description - text/plain
- folder_info
- 18kB
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