Genetic predisposition to ductal carcinoma in situ of the breast
Petridis, C, Brook, MN, Shah, V, Kohut, K, Gorman, P, Caneppele, M, Levi, D, Papouli, E, Orr, N, Cox, A, Cross, SS, Dos santos silva, I
, Peto, J, Swerdlow, A, Schoemaker, MJ, Bolla, MK, Wang, Q, Dennis, J, Michailidou, K, Benitez, J, González-Neira, A, Tessier, DC, Vincent, D, Li, J, Figueroa, J, Kristensen, V, Borresen-Dale, A, Soucy, P, Simard, J, Milne, RL, Giles, GG, Margolin, S, Lindblom, A, Brüning, T, Brauch, H, Southey, MC, Hopper, JL, Dörk, T, Bogdanova, NV, Kabisch, M, Hamann, U, Schmutzler, RK, Meindl, A, Brenner, H, Arndt, V, Winqvist, R, Pylkäs, K, Fasching, PA, Beckmann, MW, Lubinski, J, Jakubowska, A, Mulligan, AM, Andrulis, IL, Tollenaar, Rob A. E. M., Devilee, P, Le Marchand, L, Haiman, CA, Mannermaa, A, Kosma, V, Radice, P, Peterlongo, P, Marme, F, Burwinkel, B, van Deurzen, CHM, Hollestelle, A, Miller, N, Kerin, MJ, Lambrechts, D, Floris, G, Wesseling, J, Flyger, H, Bojesen, SE, Yao, S, Ambrosone, CB, Chenevix-Trench, G, Truong, T, Guénel, P, Rudolph, A, Chang-Claude, J, Nevanlinna, H, Blomqvist, C, Czene, K, Brand, JS, Olson, JE, Couch, FJ, Dunning, AM, Hall, P, Easton, DF, Pharoah, PDP, Pinder, SE, Schmidt, MK, Tomlinson, I, Roylance, R, García-Closas, M and Sawyer, EJ
(2016).
Genetic predisposition to ductal carcinoma in situ of the breast.
[Dataset].
Breast Cancer Research.
10.1186/s13058-016-0675-7.
, Peto, J, Swerdlow, A, Schoemaker, MJ, Bolla, MK, Wang, Q, Dennis, J, Michailidou, K, Benitez, J, González-Neira, A, Tessier, DC, Vincent, D, Li, J, Figueroa, J, Kristensen, V, Borresen-Dale, A, Soucy, P, Simard, J, Milne, RL, Giles, GG, Margolin, S, Lindblom, A, Brüning, T, Brauch, H, Southey, MC, Hopper, JL, Dörk, T, Bogdanova, NV, Kabisch, M, Hamann, U, Schmutzler, RK, Meindl, A, Brenner, H, Arndt, V, Winqvist, R, Pylkäs, K, Fasching, PA, Beckmann, MW, Lubinski, J, Jakubowska, A, Mulligan, AM, Andrulis, IL, Tollenaar, Rob A. E. M., Devilee, P, Le Marchand, L, Haiman, CA, Mannermaa, A, Kosma, V, Radice, P, Peterlongo, P, Marme, F, Burwinkel, B, van Deurzen, CHM, Hollestelle, A, Miller, N, Kerin, MJ, Lambrechts, D, Floris, G, Wesseling, J, Flyger, H, Bojesen, SE, Yao, S, Ambrosone, CB, Chenevix-Trench, G, Truong, T, Guénel, P, Rudolph, A, Chang-Claude, J, Nevanlinna, H, Blomqvist, C, Czene, K, Brand, JS, Olson, JE, Couch, FJ, Dunning, AM, Hall, P, Easton, DF, Pharoah, PDP, Pinder, SE, Schmidt, MK, Tomlinson, I, Roylance, R, García-Closas, M and Sawyer, EJ
(2016).
Genetic predisposition to ductal carcinoma in situ of the breast.
[Dataset].
Breast Cancer Research.
10.1186/s13058-016-0675-7.
Data associated with a study on the shared genetic susceptibility for Ductal carcinoma in situ (DCIS) and Invasive Ductal Carcinoma (IDC).
Keywords
Ductal carcinoma in situ, Association study, Genetic predisposition, Common variants| Item Type | Dataset |
|---|---|
| Capture method | Aggregation |
| Date | 17 February 2016 |
| Language(s) of written materials | English |
| Creator(s) |
Petridis, C, Brook, MN, Shah, V, Kohut, K, Gorman, P, Caneppele, M, Levi, D, Papouli, E, Orr, N, Cox, A, Cross, SS, Dos santos silva, I, Peto, J, Swerdlow, A, Schoemaker, MJ, Bolla, MK, Wang, Q, Dennis, J, Michailidou, K, Benitez, J, González-Neira, A, Tessier, DC, Vincent, D, Li, J, Figueroa, J, Kristensen, V, Borresen-Dale, A, Soucy, P, Simard, J, Milne, RL, Giles, GG, Margolin, S, Lindblom, A, Brüning, T, Brauch, H, Southey, MC, Hopper, JL, Dörk, T, Bogdanova, NV, Kabisch, M, Hamann, U, Schmutzler, RK, Meindl, A, Brenner, H, Arndt, V, Winqvist, R, Pylkäs, K, Fasching, PA, Beckmann, MW, Lubinski, J, Jakubowska, A, Mulligan, AM, Andrulis, IL, Tollenaar, Rob A. E. M., Devilee, P, Le Marchand, L, Haiman, CA, Mannermaa, A, Kosma, V, Radice, P, Peterlongo, P, Marme, F, Burwinkel, B, van Deurzen, CHM, Hollestelle, A, Miller, N, Kerin, MJ, Lambrechts, D, Floris, G, Wesseling, J, Flyger, H, Bojesen, SE, Yao, S, Ambrosone, CB, Chenevix-Trench, G, Truong, T, Guénel, P, Rudolph, A, Chang-Claude, J, Nevanlinna, H, Blomqvist, C, Czene, K, Brand, JS, Olson, JE, Couch, FJ, Dunning, AM, Hall, P, Easton, DF, Pharoah, PDP, Pinder, SE, Schmidt, MK, Tomlinson, I, Roylance, R, García-Closas, M and Sawyer, EJ
|
| LSHTM Faculty/Department | Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology |
| Participating Institutions | Study consortium |
| Funders |
Project Funder Grant Number Funder URI |
| Date Deposited | 25 Feb 2016 10:43 |
| Last Modified | 09 Jul 2021 11:22 |
| Publisher | Breast Cancer Research |
AdditionalFile-01_MSWord.docx
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subject - Data
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Study information for the Breast Cancer Association Consortium ( BCAC ) participating studies
description - application/vnd.openxmlformats-officedocument.wordprocessingml.document
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- 29kB
AdditionalFile-02_MSWord.docx
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subject - Data
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- Available under Creative Commons: Attribution 3.0
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info - Sample information for the SEARCH, UKBGS, SBCS, and BBCS studies
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- 16kB
AdditionalFile-03_Excel.xlsx
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subject - Data
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Number of studies and individuals included in analyses of ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC)
grid_on - application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
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- 13kB
AdditionalFile-04_PDF.pdf
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subject - Graphical representation of data
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- Available under Creative Commons: Attribution 3.0
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info - Principal component analysis (PCA) results from the study to investigate the genetics of in situ carcinoma of the ductal subtype (ICICLE)
picture_as_pdf - application/pdf
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AdditionalFile-05_PDF.pdf
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subject - Graphical representation of data
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Quantile-quantile plots from the study to investigate the genetics of in situ carcinoma of the ductal subtype (ICICLE ).SNP single nucleotide polymorphism
picture_as_pdf - application/pdf
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AdditionalFile-06_MSWord.docx
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subject - Data
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Grade, estrogen receptor (ER) status, and age groups in patients with ductal carcinoma in situ (DCIS)
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AdditionalFile-07_Excel.xlsx
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subject - Data
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Association between ductal carcinoma in situ (DCIS) and known breast cancer predisposition loci.IDC invasive ductal carcinoma, P-Het P value for heterogeneity, SNP single nucleotide polymorphism, OR odds ratio
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AdditionalFile-08_Excel.xlsx
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subject - Data
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- Available under Creative Commons: Attribution 3.0
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info - Age-specific case-only analysis of patients with ductal carcinoma in situ (DCIS) diagnosed at age <50 vs ≥50 years.P-Het P value for heterogeneity, SNP single nucleotide polymorphism, OR odds ratio
grid_on - application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
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AdditionalFile-09_Excel.xlsx
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subject - Data
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Associations between the known breast cancer predisposition loci and estrogen receptor-positive (ER+) or ER– ductal carcinoma in situ (DCIS) .P-Het P value for heterogeneity, SNP single nucleotide polymorphism, OR odds ratio
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AdditionalFile-10a-PDF.pdf
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subject - Graphical representation of data
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- Available under Creative Commons: Attribution 3.0
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info - Known breast cancer predisposition loci for low/intermediate grade (black) and high grade ductal carcinoma in situ (DCIS) (gray)
picture_as_pdf - application/pdf
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AdditionalFile-10b-PDF.pdf
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subject - Graphical representation of data
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Due to the large number of single nucleotide polymorphisms (SNPs), the plot is split for better visual representation into two different sections (a and b) with a descending order of effect size for the low/intermediate group. OR odds ratio
picture_as_pdf - application/pdf
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AdditionalFile-11_Excel.xlsx
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subject - Data
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- Available under Creative Commons: Attribution 3.0
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info - Associations of the known breast cancer predisposition loci for high and low-intermediate grade ductal carcinoma in situ (DCIS) .P-Het P value for heterogeneity, OR odds ratio
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AdditionalFile-12_Excel.xlsx
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subject - Data
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- Available under Creative Commons: Attribution 3.0
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info - Association of rs75915166 and rs554219 with grade in invasive ductal carcinoma ( IDC ).P-Het P value for heterogeneity, OR odds ratio
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AdditionalFile-13_Excel.xlsx
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subject - Data
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info - Associations between the known and novel breast cancer predisposition loci and invasive ductal cancer, by estrogen receptor ( ER ) status and grade.OR odds ratio
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AdditionalFile-14_Excel.xlsx
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subject - Data
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info - Association between the known breast cancer predisposition loci and estrogen receptor-positive (ER+) ductal carcinoma in situ (DCIS) or lobular carcinoma in situ (LCIS) .P-Het P value for heterogeneity, SNP single nucleotide polymorphism, OR odds ratio
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