Genetic predisposition to ductal carcinoma in situ of the breast
Petridis, C; Brook, MN; Shah, V; Kohut, K; Gorman, P; Caneppele, M; Levi, D; Papouli, E; Orr, N; Cox, A; Cross, SS; Dos santos silva, I
; Peto, J; Swerdlow, A; Schoemaker, MJ; Bolla, MK; Wang, Q; Dennis, J; Michailidou, K; Benitez, J; González-Neira, A; Tessier, DC; Vincent, D; Li, J; Figueroa, J; Kristensen, V; Borresen-Dale, A; Soucy, P; Simard, J; Milne, RL; Giles, GG; Margolin, S; Lindblom, A; Brüning, T; Brauch, H; Southey, MC; Hopper, JL; Dörk, T; Bogdanova, NV; Kabisch, M; Hamann, U; Schmutzler, RK; Meindl, A; Brenner, H; Arndt, V; Winqvist, R; Pylkäs, K; Fasching, PA; Beckmann, MW; Lubinski, J; Jakubowska, A; Mulligan, AM; Andrulis, IL; Tollenaar, Rob A. E. M.; Devilee, P; Le Marchand, L; Haiman, CA; Mannermaa, A; Kosma, V; Radice, P; Peterlongo, P; Marme, F; Burwinkel, B; van Deurzen, CHM; Hollestelle, A; Miller, N; Kerin, MJ; Lambrechts, D; Floris, G; Wesseling, J; Flyger, H; Bojesen, SE; Yao, S; Ambrosone, CB; Chenevix-Trench, G; Truong, T; Guénel, P; Rudolph, A; Chang-Claude, J; Nevanlinna, H; Blomqvist, C; Czene, K; Brand, JS; Olson, JE; Couch, FJ; Dunning, AM; Hall, P; Easton, DF; Pharoah, PDP; Pinder, SE; Schmidt, MK; Tomlinson, I; Roylance, R; García-Closas, M and Sawyer, EJ
(2016).
Genetic predisposition to ductal carcinoma in situ of the breast.
[Dataset].
Breast Cancer Research.
10.1186/s13058-016-0675-7.
; Peto, J; Swerdlow, A; Schoemaker, MJ; Bolla, MK; Wang, Q; Dennis, J; Michailidou, K; Benitez, J; González-Neira, A; Tessier, DC; Vincent, D; Li, J; Figueroa, J; Kristensen, V; Borresen-Dale, A; Soucy, P; Simard, J; Milne, RL; Giles, GG; Margolin, S; Lindblom, A; Brüning, T; Brauch, H; Southey, MC; Hopper, JL; Dörk, T; Bogdanova, NV; Kabisch, M; Hamann, U; Schmutzler, RK; Meindl, A; Brenner, H; Arndt, V; Winqvist, R; Pylkäs, K; Fasching, PA; Beckmann, MW; Lubinski, J; Jakubowska, A; Mulligan, AM; Andrulis, IL; Tollenaar, Rob A. E. M.; Devilee, P; Le Marchand, L; Haiman, CA; Mannermaa, A; Kosma, V; Radice, P; Peterlongo, P; Marme, F; Burwinkel, B; van Deurzen, CHM; Hollestelle, A; Miller, N; Kerin, MJ; Lambrechts, D; Floris, G; Wesseling, J; Flyger, H; Bojesen, SE; Yao, S; Ambrosone, CB; Chenevix-Trench, G; Truong, T; Guénel, P; Rudolph, A; Chang-Claude, J; Nevanlinna, H; Blomqvist, C; Czene, K; Brand, JS; Olson, JE; Couch, FJ; Dunning, AM; Hall, P; Easton, DF; Pharoah, PDP; Pinder, SE; Schmidt, MK; Tomlinson, I; Roylance, R; García-Closas, M and Sawyer, EJ
(2016).
Genetic predisposition to ductal carcinoma in situ of the breast.
[Dataset].
Breast Cancer Research.
10.1186/s13058-016-0675-7.
Data associated with a study on the shared genetic susceptibility for Ductal carcinoma in situ (DCIS) and Invasive Ductal Carcinoma (IDC).
Keywords
Ductal carcinoma in situ; Association study; Genetic predisposition; Common variants| Item Type | Dataset |
|---|---|
| Resource Type |
Resource Type Resource Description Dataset Quantitative |
| Capture method | Aggregation |
| Date | 17 February 2016 |
| Language(s) of written materials | English |
| Creator(s) |
Petridis, C; Brook, MN; Shah, V; Kohut, K; Gorman, P; Caneppele, M; Levi, D; Papouli, E; Orr, N; Cox, A; Cross, SS; Dos santos silva, I; Peto, J; Swerdlow, A; Schoemaker, MJ; Bolla, MK; Wang, Q; Dennis, J; Michailidou, K; Benitez, J; González-Neira, A; Tessier, DC; Vincent, D; Li, J; Figueroa, J; Kristensen, V; Borresen-Dale, A; Soucy, P; Simard, J; Milne, RL; Giles, GG; Margolin, S; Lindblom, A; Brüning, T; Brauch, H; Southey, MC; Hopper, JL; Dörk, T; Bogdanova, NV; Kabisch, M; Hamann, U; Schmutzler, RK; Meindl, A; Brenner, H; Arndt, V; Winqvist, R; Pylkäs, K; Fasching, PA; Beckmann, MW; Lubinski, J; Jakubowska, A; Mulligan, AM; Andrulis, IL; Tollenaar, Rob A. E. M.; Devilee, P; Le Marchand, L; Haiman, CA; Mannermaa, A; Kosma, V; Radice, P; Peterlongo, P; Marme, F; Burwinkel, B; van Deurzen, CHM; Hollestelle, A; Miller, N; Kerin, MJ; Lambrechts, D; Floris, G; Wesseling, J; Flyger, H; Bojesen, SE; Yao, S; Ambrosone, CB; Chenevix-Trench, G; Truong, T; Guénel, P; Rudolph, A; Chang-Claude, J; Nevanlinna, H; Blomqvist, C; Czene, K; Brand, JS; Olson, JE; Couch, FJ; Dunning, AM; Hall, P; Easton, DF; Pharoah, PDP; Pinder, SE; Schmidt, MK; Tomlinson, I; Roylance, R; García-Closas, M and Sawyer, EJ
|
| LSHTM Faculty/Department | Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology |
| Participating Institutions | Study consortium |
| Funders |
Project Funder Grant Number Funder URI |
| Date Deposited | 25 Feb 2016 10:43 |
| Last Modified | 09 Jul 2021 11:22 |
| Publisher | Breast Cancer Research |
Data / Code
AdditionalFile-01_MSWord.docx
-
subject - Data
-
- Available under Creative Commons: Attribution 3.0
-
info - Study information for the Breast Cancer Association Consortium ( BCAC ) participating studies
description - application/vnd.openxmlformats-officedocument.wordprocessingml.document
- folder_info
- 29kB
AdditionalFile-02_MSWord.docx
-
subject - Data
-
- Available under Creative Commons: Attribution 3.0
-
info - Sample information for the SEARCH, UKBGS, SBCS, and BBCS studies
description - application/vnd.openxmlformats-officedocument.wordprocessingml.document
- folder_info
- 16kB
AdditionalFile-03_Excel.xlsx
-
subject - Data
-
- Available under Creative Commons: Attribution 3.0
-
info - Number of studies and individuals included in analyses of ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC)
grid_on - application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
- folder_info
- 13kB
AdditionalFile-06_MSWord.docx
-
subject - Data
-
- Available under Creative Commons: Attribution 3.0
-
info - Grade, estrogen receptor (ER) status, and age groups in patients with ductal carcinoma in situ (DCIS)
description - application/vnd.openxmlformats-officedocument.wordprocessingml.document
- folder_info
- 16kB
AdditionalFile-07_Excel.xlsx
-
subject - Data
-
- Available under Creative Commons: Attribution 3.0
-
info - Association between ductal carcinoma in situ (DCIS) and known breast cancer predisposition loci.IDC invasive ductal carcinoma, P-Het P value for heterogeneity, SNP single nucleotide polymorphism, OR odds ratio
grid_on - application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
- folder_info
- 20kB
AdditionalFile-08_Excel.xlsx
-
subject - Data
-
- Available under Creative Commons: Attribution 3.0
-
info - Age-specific case-only analysis of patients with ductal carcinoma in situ (DCIS) diagnosed at age <50 vs ≥50 years.P-Het P value for heterogeneity, SNP single nucleotide polymorphism, OR odds ratio
grid_on - application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
- folder_info
- 17kB
AdditionalFile-09_Excel.xlsx
-
subject - Data
-
- Available under Creative Commons: Attribution 3.0
-
info - Associations between the known breast cancer predisposition loci and estrogen receptor-positive (ER+) or ER– ductal carcinoma in situ (DCIS) .P-Het P value for heterogeneity, SNP single nucleotide polymorphism, OR odds ratio
grid_on - application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
- folder_info
- 19kB
AdditionalFile-11_Excel.xlsx
-
subject - Data
-
- Available under Creative Commons: Attribution 3.0
-
info - Associations of the known breast cancer predisposition loci for high and low-intermediate grade ductal carcinoma in situ (DCIS) .P-Het P value for heterogeneity, OR odds ratio
grid_on - application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
- folder_info
- 19kB
AdditionalFile-12_Excel.xlsx
-
subject - Data
-
- Available under Creative Commons: Attribution 3.0
-
info - Association of rs75915166 and rs554219 with grade in invasive ductal carcinoma ( IDC ).P-Het P value for heterogeneity, OR odds ratio
grid_on - application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
- folder_info
- 9kB
AdditionalFile-13_Excel.xlsx
-
subject - Data
-
- Available under Creative Commons: Attribution 3.0
-
info - Associations between the known and novel breast cancer predisposition loci and invasive ductal cancer, by estrogen receptor ( ER ) status and grade.OR odds ratio
grid_on - application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
- folder_info
- 25kB
AdditionalFile-14_Excel.xlsx
-
subject - Data
-
- Available under Creative Commons: Attribution 3.0
-
info - Association between the known breast cancer predisposition loci and estrogen receptor-positive (ER+) ductal carcinoma in situ (DCIS) or lobular carcinoma in situ (LCIS) .P-Het P value for heterogeneity, SNP single nucleotide polymorphism, OR odds ratio
grid_on - application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
- folder_info
- 20kB
Data Visualisation
AdditionalFile-04_PDF.pdf
-
subject - Graphical representation of data
-
- Available under Creative Commons: Attribution 3.0
-
info - Principal component analysis (PCA) results from the study to investigate the genetics of in situ carcinoma of the ductal subtype (ICICLE)
picture_as_pdf - application/pdf
- folder_info
- 258kB
AdditionalFile-05_PDF.pdf
-
subject - Graphical representation of data
-
- Available under Creative Commons: Attribution 3.0
-
info - Quantile-quantile plots from the study to investigate the genetics of in situ carcinoma of the ductal subtype (ICICLE ).SNP single nucleotide polymorphism
picture_as_pdf - application/pdf
- folder_info
- 204kB
AdditionalFile-10a-PDF.pdf
-
subject - Graphical representation of data
-
- Available under Creative Commons: Attribution 3.0
-
info - Known breast cancer predisposition loci for low/intermediate grade (black) and high grade ductal carcinoma in situ (DCIS) (gray)
picture_as_pdf - application/pdf
- folder_info
- 14kB
AdditionalFile-10b-PDF.pdf
-
subject - Graphical representation of data
-
- Available under Creative Commons: Attribution 3.0
-
info - Due to the large number of single nucleotide polymorphisms (SNPs), the plot is split for better visual representation into two different sections (a and b) with a descending order of effect size for the low/intermediate group. OR odds ratio
picture_as_pdf - application/pdf
- folder_info
- 13kB
Downloads
