Autopsy Prevalence of Tuberculosis and Other Potentially Treatable Infections among Adults with Advanced HIV Enrolled in Out-Patient Care in South Africa: Lesedi Kamoso study data

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Karat, AS, Omar, T, von Gottberg, A, Tlali, M, Chihota, VN, Churchyard, GJ, Fielding, KL, Johnson, S, Martinson, NA, McCarthy, K, Wolter, N, Wong, EB, Charalambous, S and Grant, AD. 2016. Autopsy Prevalence of Tuberculosis and Other Potentially Treatable Infections among Adults with Advanced HIV Enrolled in Out-Patient Care in South Africa: Lesedi Kamoso study data. [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: 10.17037/DATA.122

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Early mortality among HIV-positive adults starting antiretroviral therapy (ART) remains high in resource-limited settings, with tuberculosis (TB) the leading cause of death. However, current methods to estimate TB-related deaths are inadequate and most autopsy studies do not adequately represent those attending primary health clinics (PHCs). The TB Fast Track study aimed to determine the autopsy prevalence of TB and other infections in adults enrolled at South African PHCs in the context of a pragmatic trial of empiric TB treatment. This dataset contains basic demographic information and lab investigation results of 34 HIV-positive individuals who died after study enrolment. This includes MGIT culture and Xpert MTB/RIF; aerobic and fungal cultures; and histological findings

Completed Date: 6 May 2016
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Data Creators(s): Karat, AS, Omar, T, von Gottberg, A, Tlali, M, Chihota, VN, Churchyard, GJ, Fielding, KL, Johnson, S, Martinson, NA, McCarthy, K, Wolter, N, Wong, EB, Charalambous, S and Grant, AD
LSHTM Faculty/Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Research Centre: TB Centre
Participating Institutions: London School of Hygiene & Tropical Medicine, The Aurum Institute, Johannesburg, South Africa, Foundation for Professional Development, Pretoria, South Africa, The University of the Witwatersrand, Johannesburg, South Africa, National Health Laboratory Services, South Africa, Perinatal HIV Research Unit, Soweto, Johannesburg, South Africa, Johns Hopkins Center for TB Research

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