Hensman Moss, DJ, Robertson, N, Farmer, R, Scahill, RI, Haider, S, Tessari, MA, Flynn, G, Fischer, DF, Wild, EJ, Macdonald, D and Tabrizi, SJ. 2017. Quantification of huntingtin protein species in Huntington’s disease patient leukocytes using optimised electrochemiluminescence immunoassays. [Online]. PLOS One. Available from: https://doi.org/10.1371/journal.pone.0189891
Hensman Moss, DJ, Robertson, N, Farmer, R, Scahill, RI, Haider, S, Tessari, MA, Flynn, G, Fischer, DF, Wild, EJ, Macdonald, D and Tabrizi, SJ. Quantification of huntingtin protein species in Huntington’s disease patient leukocytes using optimised electrochemiluminescence immunoassays [Internet]. PLOS One; 2017. Available from: https://doi.org/10.1371/journal.pone.0189891
Hensman Moss, DJ, Robertson, N, Farmer, R, Scahill, RI, Haider, S, Tessari, MA, Flynn, G, Fischer, DF, Wild, EJ, Macdonald, D and Tabrizi, SJ (2017). Quantification of huntingtin protein species in Huntington’s disease patient leukocytes using optimised electrochemiluminescence immunoassays. [Data Collection]. PLOS One. https://doi.org/10.1371/journal.pone.0189891
Description
Huntington’s disease (HD) is an autosomal dominant neurodegenerative condition caused by an expanded CAG repeat in the gene encoding huntingtin (HTT). Optimizing peripheral quantification of huntingtin throughout the course of HD is valuable not only to illuminate the natural history and pathogenesis of disease, but also to detect peripheral effects of drugs in clinical trial.
| Data capture method | Experiment: Laboratory |
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| Date (Date published in a 3rd party system) | 22 December 2017 |
| Language(s) of written materials | English |
| Data Creators | Hensman Moss, DJ, Robertson, N, Farmer, R, Scahill, RI, Haider, S, Tessari, MA, Flynn, G, Fischer, DF, Wild, EJ, Macdonald, D and Tabrizi, SJ |
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| LSHTM Faculty/Department | Faculty of Epidemiology and Population Health > Dept of Medical Statistics Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
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| Date Deposited | 02 Feb 2018 14:17 |
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| Last Modified | 27 Apr 2022 18:19 |
| Publisher | PLOS One |
