Missing data in trial-based cost-effectiveness analysis review dataset

Leurent, B, Gomes, M and Carpenter, J. 2017. Missing data in trial-based cost-effectiveness analysis review dataset. [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: https://doi.org/10.17037/DATA.272.

Leurent, B, Gomes, M and Carpenter, J. Missing data in trial-based cost-effectiveness analysis review dataset [Internet]. London School of Hygiene & Tropical Medicine; 2017. Available from: https://doi.org/10.17037/DATA.272.

Leurent, B, Gomes, M and Carpenter, J (2017). Missing data in trial-based cost-effectiveness analysis review dataset. [Data Collection]. London School of Hygiene & Tropical Medicine, London, United Kingdom. https://doi.org/10.17037/DATA.272.

Description

This dataset contains information extracted from studies published in the NIHR Health Technology Assessment journal between the 1st January 2013 and 31st December 2015. The study team subsequently used it as a basis to critically reviews the extent of and methods used to address missing data in recently published trial-based CEA. Detailed methodology and variables definition are reported in the accompanying Health Economics paper, “Missing data in trial-based cost-effectiveness analysis: an incomplete journey”.

Methods

Description of data capture

The PubMed database was used to identify all trial-based CEA published in HTA between the 1st January 2013 and 31st December 2015. We combined search terms such as `randomised', `trial', `cost' or `economic' to capture relevant articles (see Appendix A.1 for details of the search strategy). The full reports of these articles were downloaded, then screened for eligibility by excluding all studies that: were pilot or feasibility studies; reported costs and effects separately (e.g. cost-consequence analysis); did not report a within-trial CEA. For each included study, we extracted key information about the study and the analysis to answer our primary research questions. In a second stage, we drew on published guidelines and our experience to derive a list of recommendations to address missing data, and then re-assessed the studies to assess to which extent they followed these recommendations. Data analysis was conducted with Stata version 15.

Data capture method

Compilation/Synthesis

Data Collection Period

From	To
2016	2017

Date (Date submitted to LSHTM repository)

1 December 2017

Language(s) of written materials

English

People & Groups

Data Creators	Leurent, B, Gomes, M and Carpenter, J
LSHTM Faculty/Department	Faculty of Epidemiology and Population Health > Dept of Medical Statistics
Research Centre	Centre for Statistical Methodology
Participating Institutions	London School of Hygiene & Tropical Medicine, London, United Kingdom