Data supporting "Rural-urban differences in oral typhoid vaccine responses in Uganda: role of Schistosoma mansoni"
Nkurunungi, G
and Walusimbi, B
(2026).
Data supporting "Rural-urban differences in oral typhoid vaccine responses in Uganda: role of Schistosoma mansoni".
[Dataset].
London School of Hygiene & Tropical Medicine, London, United Kingdom.
10.17037/DATA.00005144.
and Walusimbi, B
(2026).
Data supporting "Rural-urban differences in oral typhoid vaccine responses in Uganda: role of Schistosoma mansoni".
[Dataset].
London School of Hygiene & Tropical Medicine, London, United Kingdom.
10.17037/DATA.00005144.
This dataset comprises individual-level data from 699 participants in the POPVAC A and POPVAC C randomised controlled trials. POPVAC A was conducted among schoolchildren from Koome islands, Uganda (a schistosomiasis-endemic setting). POPVAC C was undertaken in Entebbe municipality among participants of the Entebbe Mother and Baby Study (EMaBS) cohort. Variables include data on socio-demographic characteristics, S. mansoni infection, and oral typhoid vaccine-specific plasma and copro-antibody responses.
Additional Information
To access the data, requests must be made to the POPVAC trial PI (Professor Alison Elliott) or to Dr Gyaviira Nkurunungi. The request will be reviewed by them together with the POPVAC investigator team. The request will be reviewed based on scientific value and to ensure there is no overlap with existing work. If the request is approved, before data is shared, ethics approval will need to be obtained in your host institution and a Data Transfer Agreement with the MRC/UVRI and LSHTM Uganda Research Unit must be completed.
Keywords
Oral typhoid vaccine responses; Schistosoma mansoni; Helminth infections; Copro-antibody; Uganda| Item Type | Dataset |
|---|---|
| Resource Type |
Resource Type Resource Description Dataset Quantitative |
| Capture method | Questionnaire: Fixed form, Lab observation, Measurements and tests |
| Collection Period |
From To 1 July 2019 31 December 2025 |
| Date | 1 April 2026 |
| Language(s) of written materials | English |
| Creator(s) |
Nkurunungi, G and Walusimbi, B
|
| Associated roles | Natukunda, A (Researcher); Amongin, R (Researcher); Heyraud, V (Researcher); Baine, C (Researcher); Nassuuna, J (Researcher); Webb, E (Researcher) and Elliott, AM (Researcher) |
| LSHTM Faculty/Department |
Faculty of Infectious and Tropical Diseases > Department of Infection Biology Faculty of Infectious and Tropical Diseases > Dept of Clinical Research MRC/UVRI and LSHTM Uganda Research Unit MRC/UVRI and LSHTM Uganda Research Unit > UG-Co-Infections |
| Research Group | Immunomodulation and Vaccines Group |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda |
| Funders |
Project Funder Grant Number Funder URI The impact of differential parasite exposure on immunological and metabolic predictors of vaccine response in the tropics 224263/Z/21/Z http://dx.doi.org/10.13039/100010269 |
| Date Deposited | 01 Apr 2026 17:20 |
| Last Modified | 01 Apr 2026 17:20 |
| Publisher | London School of Hygiene & Tropical Medicine |
Data / Code
Coproantibodies_data.csv
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subject - Data
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lock - Restricted to Request access for all
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copyright - Available under Data Sharing Agreement
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info - Data on S. mansoni infection, and oral typhoid vaccine responses, from the POPVAC A and C trials
description - text/plain
- folder_info
- 62B
Documentation
Coproantibodies_data_codebook.html
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subject - Documentation
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- Available under Creative Commons: Attribution 4.0
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info - Codebook for Uganda coproantibodies dataset
html - text/html
- folder_info
- 6kB
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