Effect of intra-partum azithromycin on gut microbiome development in early childhood
Medical Research Council Unit The Gambia at LSHTM (2024). Effect of intra-partum azithromycin on gut microbiome development in early childhood. [Dataset]. NIH BioProject. https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1129542
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Intrapartum azithromycin is being evaluated as a potential intervention for preventing maternal sepsis and mortality. This study evaluated the effect of intrapartum azithromycin on the development of the child gut microbiome over the first 3 years of life. The study used samples from healthy Gambian children who were recruited in the PregnAnZI-2 trial (ClinicalTrials.org NCT03199547). PregnAnZI-2 was a large clinical trial conducted in The Gambia and Burkina Faso to assess the effect of 2g oral azithromycin given to women during labour, on neonatal sepsis and mortality.

Alternative Title

PRJNA1129542

Keywords

Intrapartum azithromycin; Sepsis

Item Type Dataset
Resource Type
Resource Type
Resource Description
Dataset
Quantitative
Capture method Experiment: Laboratory
Date 28 June 2024
Language(s) of written materials English
Creator(s) Medical Research Council Unit The Gambia at LSHTM
Associated roles Sanyang, B; Camara, B; Beloum, N; Jammeh, M; Bojang, D; Mohammed, N; Sesay, AK; Roca, A and De Silva, T
LSHTM Faculty/Department MRC Unit The Gambia at LSHTM
Participating Institutions London School of Hygiene & Tropical Medicine, London, United Kingdom
Date Deposited 26 Aug 2025 10:25
Last Modified 02 Jun 2026 09:55
Publisher NIH BioProject

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