Data supporting "Temporal trends of SARS-CoV-2 exposure in adolescents: a longitudinal pilot study nested in a Uganda birth cohort"
, Natukunda, A, Nassuna, J, Nkurunungi, G, Elliott, AM and Webb, E
(2025).
Data supporting "Temporal trends of SARS-CoV-2 exposure in adolescents: a longitudinal pilot study nested in a Uganda birth cohort".
[Dataset].
London School of Hygiene & Tropical Medicine, London, United Kingdom.
10.17037/DATA.00004678.
This dataset comprises individual-level data of a subset of participants from a longitudinal study nested within the Entebbe Mother and Baby Study (EMaBS) birth cohort, based in Entebbe municipality, Uganda. Data were drawn from three studies that these participants took part in, where samples were collected: pre-pandemic samples (2014–2016) collected during a blood pressure study; pandemic-era samples collected during the POPVAC C trial (2020–2021) (ISRCTN32849447), which evaluated the impact of BCG revaccination on vaccine responses; and samples from the CoHost study (2021–2022), a 12-month longitudinal follow-up assessing SARS-CoV-2 infection and exposure from participants in the POPVAC B randomised controlled trial. The study aimed to analyse temporal trends in SARS-CoV-2 seropositivity in Ugandan adolescents using pre-pandemic (2014-2016) and pandemic-era samples (2020-2022). We utilised previously stored demographic and clinical data, along with bio-banked samples from these three studies.
Additional Information
Researchers wishing to analyse information on HIV testing and results are advised to complete a request form to contact the MRC/UVRI and LSHTM Uganda Research Unit. Data will be provided on the basis that it is stored securely and not distributed to others.
Keywords
SARS-CoV-2, Adolescents, COVID-19, Uganda, Longitudinal| Item Type | Dataset |
|---|---|
| Description of data capture | Previously stored demographic and clinical data, along with bio-banked samples, were used for this study. In the CoHost study, participants were administered a questionnaire capturing demographic information, medical history, SARS-CoV-2 exposure, and recent illness history, recorded using the research electronic data capture (REDCap) application. |
| Capture method | Questionnaire, Lab observation: Participant |
| Collection Period |
From To 2014 14 December 2022 |
| Date | 29 May 2025 |
| Language(s) of written materials | English |
| Creator(s) |
Zirimenya, L, Natukunda, A, Nassuna, J, Nkurunungi, G, Elliott, AM and Webb, E
|
| Associated roles | Zziwa, C (Researcher), Ninsiima, C (Researcher), Kukundakwe, C (Researcher), Namutebi, M (Researcher), Oduru, G (Researcher), Nsubuga, D (Researcher), Tumusiime, J (Researcher), Nakyesige, R (Researcher), Kimuda, S (Researcher), Serwanga, J (Researcher), Doores, KJ (Researcher) and Wajja, A (Researcher) |
| LSHTM Faculty/Department |
Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology & International Health (2023-) Faculty of Infectious and Tropical Diseases > Dept of Clinical Research MRC/UVRI and LSHTM Uganda Research Unit |
| Research Centre |
Malaria Centre Vaccine Centre |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom, Uganda Virus Research Institute, Entebbe, Uganda, King's College London, London, United Kingdom |
| Funders |
Project Funder Grant Number Funder URI VAnguard NIHR134531 http://dx.doi.org/10.13039/501100000272 |
| Date Deposited | 29 May 2025 16:38 |
| Last Modified | 04 Jun 2025 10:18 |
| Publisher | London School of Hygiene & Tropical Medicine |
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subject - Data
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- Available under Creative Commons: Attribution 4.0
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info - Individual-level data collected from a subset of participants from a longitudinal study nested within the Entebbe Mother and Baby Study (EMaBS) birth cohort (tab-delimited text)
description - text/plain
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- 8kB
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subject - Data
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lock - Restricted to Request access for all
- Data Sharing Agreement
- Available under Data Sharing Agreement
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info - CoHost dataset that contain additional information on HIV testing and results
description - text/plain
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subject - Documentation
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- Available under Creative Commons: Attribution 4.0
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info - Codebook for CoHost dataset
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- 30kB
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subject - Documentation
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- Available under Creative Commons: Attribution 4.0
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info - User guide for CoHost dataset
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