ERASE-TB: prediction models for Mtb infection dataset

Calderwood, C, Marambire, E and Kranzer, K. 2025. ERASE-TB: prediction models for Mtb infection dataset. [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: https://doi.org/10.17037/DATA.00004571.

Calderwood, C, Marambire, E and Kranzer, K. ERASE-TB: prediction models for Mtb infection dataset [Internet]. London School of Hygiene & Tropical Medicine; 2025. Available from: https://doi.org/10.17037/DATA.00004571.

Calderwood, C, Marambire, E and Kranzer, K (2025). ERASE-TB: prediction models for Mtb infection dataset. [Data Collection]. London School of Hygiene & Tropical Medicine, London, United Kingdom. https://doi.org/10.17037/DATA.00004571.

Description

Data from the ERASE-TB study, used to develop prediction models for Mtb infection among adolescent and adult tuberculosis household contacts and evaluate the risk of Mtb infection by HIV status. This is a cross-sectional dataset, with one row per person, indicating the participant interferon gamma release assay status, demographics and clinical history, and data on the index person with tuberculosis in the household (index case) and household-level variables. All candidate predictors for prediction model development are included.

Methods

Data capture method

Questionnaire, Measurements and tests

Data Collection Period

From	To
1 March 2021	31 March 2021

Date (Completed)

3 March 2025

Language(s) of written materials

English

People & Groups

Data Creators	Calderwood, C, Marambire, E and Kranzer, K
Associated roles	Kranzer, K (Principal Investigator), Marambire, E (Work Package Leader) and Larsson, L (Data Manager)
LSHTM Faculty/Department	Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Research Centre	TB Centre
Research Group	The Health Research Unit Zimbabwe
Participating Institutions	London School of Hygiene & Tropical Medicine, London, United Kingdom, LMU University of Munich, Munich, Germany, Biomedical Research and Training Institute, National Institute for Medical Research (MMRC - Mbeya), Mbeya, Tanzania, Instituto Nacional de Saúde

Projects

Funders

Project	Funder	Grant Number	Funder URI
ERASE-TB	European and Developing Countries Clinical Trials Partnership	RIA2018D-2508	http://dx.doi.org/10.13039/501100001713
IMBA Hutano	Wellcome Trust	225466/Z/22/Z	http://dx.doi.org/10.13039/100010269
ERASE-TB	Deutsches Zentrum für Infektionsforschung	TTU 02.912_00	https://doi.org/10.13039/100009139