Uganda Liver Disease study – Dataset for analysis of liver, metabolic and cardiovascular parameters associated with mortality in the General Population Cohort

Newton, R, Matthews, P, Campbell, C, Mugisha, J, Kimono, B, Waddilove, E, Makanga, R, Wang, T, Seeley, J and Muzaale, FN. 2025. Uganda Liver Disease study – Dataset for analysis of liver, metabolic and cardiovascular parameters associated with mortality in the General Population Cohort. [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: https://doi.org/10.17037/DATA.00004497.

Newton, R, Matthews, P, Campbell, C, Mugisha, J, Kimono, B, Waddilove, E, Makanga, R, Wang, T, Seeley, J and Muzaale, FN. Uganda Liver Disease study – Dataset for analysis of liver, metabolic and cardiovascular parameters associated with mortality in the General Population Cohort [Internet]. London School of Hygiene & Tropical Medicine; 2025. Available from: https://doi.org/10.17037/DATA.00004497.

Newton, R, Matthews, P, Campbell, C, Mugisha, J, Kimono, B, Waddilove, E, Makanga, R, Wang, T, Seeley, J and Muzaale, FN (2025). Uganda Liver Disease study – Dataset for analysis of liver, metabolic and cardiovascular parameters associated with mortality in the General Population Cohort. [Data Collection]. London School of Hygiene & Tropical Medicine, London, United Kingdom. https://doi.org/10.17037/DATA.00004497.

Description

This dataset contains information collected through the Uganda General Population Cohort (GPC) that was used by the Uganda Liver Disease study to assess how liver, metabolic and cardiovascular parameters are associated with all-cause mortality. This includes data on liver function tests (serum AST, ALT, ALP, GGT and BR) obtained in survey rounds 22 (years 2010-11) and 24 (years 2013-14); metabolic biomarkers (hemoglobin A1c, high density lipoprotein, low density lipoprotein, and triglycerides) collected in round 22 (2010-11); screening results for Human Immunodeficiency Virus (HIV) and Hepatitis B Virus (HBV) infection that were obtained in survey round 22, and follow-up data for mortality analyses collected up to study round 34 (2022-23). Death was ascertained through mortality registers and verbal autopsy.

Methods

Data capture method

Measurements and tests

Data Collection Period

From	To
2010	2023

Date (Completed)

1 April 2025

Language(s) of written materials

English

People & Groups

Data Creators	Newton, R, Matthews, P, Campbell, C, Mugisha, J, Kimono, B, Waddilove, E, Makanga, R, Wang, T, Seeley, J and Muzaale, FN
LSHTM Faculty/Department	Faculty of Public Health and Policy > Dept of Global Health and Development Faculty of Public Health and Policy > Dept of Health Services Research and Policy MRC/UVRI and LSHTM Uganda Research Unit
Participating Institutions	London School of Hygiene & Tropical Medicine, London, United Kingdom

Projects

Funders

Project	Funder	Grant Number	Funder URI
Liver, cardiovascular and metabolic factors as predictors of all-cause mortality in a rural Ugandan Cohort	John Fell Fund, University of Oxford	UNSPECIFIED	https://doi.org/10.13039/501100004789
Liver, cardiovascular and metabolic factors as predictors of all-cause mortality in a rural Ugandan Cohort	Medical Research Council	UNSPECIFIED	https://doi.org/10.13039/501100000265