Multimodal mucosal and systemic immune characterization of a non-human primate trachoma model highlights the critical role of local immunity during acute phase disease

This dataset contains results characterizing our model of trachoma (non-human primate). Those results comprise clinical scoring to assess the clinical signs, bacterial quantification to assess the conjunctival infection by Chlamydia trachomatis, as well as local and systemic immune assessment (conjunctival immune population with flow cytometry, immunoglobulin, and cytokines quantifications). Results are organized by type of data, each data type in a different folder. Clinical scoring is compiled in a single Excel file of clinical scoring results (on a scale of 0 to 8 for total scoring, 0 to 3 for inflammation score, and 0 to 5 for follicles score). Bacterial loads of conjunctival Chlamydia trachomatis are compiled in a single Excel file with qPCR results expressed in equivalent copies of IFU (inclusion forming unit) per µL. Flow cytometry results are put as FCS files raw from any analysis with a separate folder for each timepoint and a different folder for compensation files. Each animal is a different FCS file. Cytokine quantifications are compiled in a single Excel file. Each cytokine is expressed in pg per µL. Immunoglobulin quantifications are compiled in a single Excel file and expressed in titers. For every Excel file, cells were left blank when the data wasn't available.

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