The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination
Beilinson, H
; Yadavalli, A; Xiao, J; Corbett, L; Saribasak, H and Schatz, D
(2021).
The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination.
[Dataset].
NCBI Gene Expression Omnibus.
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE180734
; Yadavalli, A; Xiao, J; Corbett, L; Saribasak, H and Schatz, D
(2021).
The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination.
[Dataset].
NCBI Gene Expression Omnibus.
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE180734
Studies of novel RAG1 N-terminal region mutants reveal a role for the first 215 amino acids in establishing the balance between short- and long-range V(D)J recombination and a distinct role for RAG1 ubiquitin ligase activity in promoting efficient recombination and lymphocyte development.
Keywords
Mice| Item Type | Dataset |
|---|---|
| Resource Type |
Resource Type Resource Description Dataset Quantitative |
| Capture method | Experiment: Laboratory |
| Date | 26 July 2021 |
| Language(s) of written materials | English |
| Creator(s) |
Beilinson, H; Yadavalli, A; Xiao, J; Corbett, L; Saribasak, H and Schatz, D
|
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Clinical Research |
| Participating Institutions | London School of Hygiene & Tropical Medicine |
| Date Deposited | 08 Aug 2023 12:53 |
| Last Modified | 28 Oct 2025 16:17 |
| Publisher | NCBI Gene Expression Omnibus |
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