Beilinson, H, Yadavalli, A, Xiao, J, Corbett, L, Saribasak, H and Schatz, D. 2021. The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination. [Online]. NCBI Gene Expression Omnibus. Available from: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE180734
Beilinson, H, Yadavalli, A, Xiao, J, Corbett, L, Saribasak, H and Schatz, D. The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination [Internet]. NCBI Gene Expression Omnibus; 2021. Available from: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE180734
Beilinson, H, Yadavalli, A, Xiao, J, Corbett, L, Saribasak, H and Schatz, D (2021). The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination. [Data Collection]. NCBI Gene Expression Omnibus. https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE180734
Description
Studies of novel RAG1 N-terminal region mutants reveal a role for the first 215 amino acids in establishing the balance between short- and long-range V(D)J recombination and a distinct role for RAG1 ubiquitin ligase activity in promoting efficient recombination and lymphocyte development.
Keywords
| Data capture method | Experiment: Laboratory |
|---|---|
| Date (Date published in a 3rd party system) | 26 July 2021 |
| Language(s) of written materials | English |
| Data Creators | Beilinson, H, Yadavalli, A, Xiao, J, Corbett, L, Saribasak, H and Schatz, D |
|---|---|
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Clinical Research |
| Participating Institutions | London School of Hygiene & Tropical Medicine |
| Date Deposited | 08 Aug 2023 12:53 |
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| Last Modified | 08 Aug 2023 12:53 |
| Publisher | NCBI Gene Expression Omnibus |
