Computer Aided Screening for Tuberculosis in Low Resource Environments (CASTLE) trial data
(2024).
Computer Aided Screening for Tuberculosis in Low Resource Environments (CASTLE) trial data.
[Dataset].
London School of Hygiene & Tropical Medicine, London, United Kingdom.
10.17037/DATA.00003552.
CASTLE is a cluster randomised trial comparing enhanced TB diagnostics (urine SILVAMP-LAM plus urine LF-LAM plus digital chest Xray with computer aided diagnosis plus usual care) to usual care alone, among adults living with HIV admitted to hospital. Clusters are day of admission to hospital. Primary outcome is TB treatment started prior to hospital discharge. Secondary outcomes are all-cause mortality at 56 days from enrolment, undiagnosed TB at time of discharge from hospital, and TB treatment initiation within 24 hours of enrolment. Data was collected using a combination of face-to-face questionnaire, laboratory test results, and information gathered from written medical records by trained research assistants.
Keywords
Tuberculosis, TB diagnostics, HIV| Item Type | Dataset |
|---|---|
| Description of data capture | Data collected using a combination of face-to-face questionnaire, laboratory test results, and information gathered from written medical records by trained research assistants. |
| Capture method | Questionnaire, Aggregation, Physical measurements and tests |
| Collection Period |
From To 5 September 2020 31 March 2022 |
| Date | 8 March 2024 |
| Language(s) of written materials | English |
| Creator(s) |
Burke, R
|
| Associated roles | MacPherson, P (Co-Investigator) and Corbett, EL (Co-Investigator) |
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Clinical Research |
| Research Centre | TB Centre |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom, Malawi Liverpool Wellcome Research Programme, Blantyre, Malawi |
| Funders |
Project Funder Grant Number Funder URI Computer Aided Screening for Tuberculosis in Low Resource Environments (CASTLE) 203905/Z/16/Z http://dx.doi.org/10.13039/100010269 |
| Date Deposited | 08 Mar 2024 11:35 |
| Last Modified | 08 Mar 2024 11:37 |
| Publisher | London School of Hygiene & Tropical Medicine |
-
subject - Data
-
- Available under Creative Commons: Attribution 4.0
-
info - Stata DO file for trial analysis
code - text/x-java
- folder_info
- 3kB
-
subject - Data
-
lock - Restricted to Request access for all
- Data Sharing Agreement
- Available under Data Sharing Agreement
-
info - Data related to participants in cohort
description - text/plain
- folder_info
- 67B
-
subject - Data
-
lock - Restricted to Request access for all
- Data Sharing Agreement
- Available under Data Sharing Agreement
-
info - Data related to trial participants
description - text/plain
- folder_info
- 67B
-
subject - Documentation
-
- Available under Creative Commons: Attribution 4.0
-
info - Codebook for cohort and trial participant datasets
html - text/html
- folder_info
- 42kB
