MBIRA - Mortality from Bacterial Infections Resistant to Antibiotics study - underlying data
Antimicrobial resistance is a major global health concern, but there is limited data linking laboratory resistance testing to clinical outcomes, especially from Low-and-Middle-Income countries, including African nations. This is a project collecting prospective data about bloodstream infections caused by Enterobacterales bacteria in African hospitals in 2020-22. A central focus was the impact of 3rd generation cephalosporin (3GC) resistance on patient mortality. In the main study, n=8 hospitals in eight different countries contributed to this project. Preliminary work involved collection of descriptive information from these 8 hospitals, including access to antibiotics in hospital pharmacies. Information was collected for infected patients and matched non-infected patients in same hospitals.
The MBIRA study collected data about hospitals, patients, bacterial isolates and antibiotic use. The “mbira_hospital” dataset contains information collected as a one-off event as part of the “hospital” form and the “mbira_pharmacy” contains information on antibiotic availability in pharmacies that were collected each month. Further datasets will be made available at a later date.
Additional Information
Version 1 of the ‘mbira_pharmacy_data’ dataset was available between Jan 9 - 23, 2023. This was replaced with 'mbira_pharmacy_v2' on Jan 23 2023, which contains an additional table containing collapsed data for scatter plot.
Keywords
Antimicrobial resistance, clinical outcomes, Enterobacterales, Bacteria, LMICItem Type | Dataset |
---|---|
Capture method | Questionnaire |
Collection Period |
From To 2 March 2020 31 March 2023 |
Date | 9 January 2023 |
Geographical area covered (offline during plugin upgrade) |
North Latitude East Longitude South Latitude West Longitude 15.2743 54.4812 -35.3974 -23.5657 |
Language(s) of written materials | English |
Creator(s) |
Aiken, A |
Associated roles | Rehman, AM (Co-Investigator) |
LSHTM Faculty/Department | Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology (-2023) |
Research Centre | Antimicrobial Resistance Centre (AMR) |
Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom, Stellenbosch University, South Africa, KEMRI-Wellcome Trust, Kenya, University of Ghana Medical School, Ghana, Centre for Infectious Diseases Research in Zambia, Zambia, Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Malawi, Haramaya University, Ethiopia, National Hospital Abuja, Nigeria |
Funders |
Project Funder Grant Number Funder URI Mortality from Bacterial Infections Resistant to Antibiotics (MBIRA) INV-003519 http://dx.doi.org/10.13039/100000865 |
Date Deposited | 09 Jan 2023 15:26 |
Last Modified | 23 Jun 2023 11:29 |
Publisher | London School of Hygiene & Tropical Medicine |
-
subject - Data
-
- Available under Creative Commons: Attribution 4.0
-
info - Data collected as part of a cross-sectional survey in hospitals conducted at the start of the MBIRA study
grid_on - application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
- folder_info
- 13kB
-
subject - Data
-
- Available under Creative Commons: Attribution 4.0
-
info - Data collected as part of a cross-sectional survey on on antibiotic availability in hospital pharmacies
grid_on - application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
- folder_info
- 22kB
-
subject - Data
-
lock - Restricted to Request access for all
- Data Sharing Agreement
- Available under Data Sharing Agreement
-
info - Please contact the study authors directly in relation to other study data
description - text/plain
- folder_info
- 80B
-
subject - Documentation
-
- Available under Creative Commons: Attribution 4.0
-
info - MBIRA data codebook
html - text/html
- folder_info
- 18kB