MBIRA - Mortality from Bacterial Infections Resistant to Antibiotics study - underlying data

Aiken, AORCID logo and Rehman, AMORCID logo (2023). MBIRA - Mortality from Bacterial Infections Resistant to Antibiotics study - underlying data. [Dataset]. London School of Hygiene & Tropical Medicine, London, United Kingdom. 10.17037/DATA.00003168.
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Antimicrobial resistance is a major global health concern, but there is limited data linking laboratory resistance testing to clinical outcomes, especially from Low-and-Middle-Income countries, including African nations. This is a project collecting prospective data about bloodstream infections caused by Enterobacterales bacteria in African hospitals in 2020-22. A central focus was the impact of 3rd generation cephalosporin (3GC) resistance on patient mortality. In the main study, n=8 hospitals in eight different countries contributed to this project. Preliminary work involved collection of descriptive information from these 8 hospitals, including access to antibiotics in hospital pharmacies. Information was collected for infected patients and matched non-infected patients in same hospitals. The MBIRA study collected data about hospitals, patients, bacterial isolates and antibiotic use. The “mbira_hospital” dataset contains information collected as a one-off event as part of the “hospital” form and the “mbira_pharmacy” contains information on antibiotic availability in pharmacies that were collected each month. Further datasets will be made available at a later date.

Additional Information

Version 1 of the ‘mbira_pharmacy_data’ dataset was available between Jan 9 - 23, 2023. This was replaced with 'mbira_pharmacy_v2' on Jan 23 2023, which contains an additional table containing collapsed data for scatter plot.

Keywords

Antimicrobial resistance, clinical outcomes, Enterobacterales, Bacteria, LMIC

mbira_hospital_data.xlsx
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Data
Available under Creative Commons: Attribution 4.0
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Data collected as part of a cross-sectional survey in hospitals conducted at the start of the MBIRA study
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mbira_pharmacy_v2.xlsx
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Data
Available under Creative Commons: Attribution 4.0
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Data collected as part of a cross-sectional survey on on antibiotic availability in hospital pharmacies
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22kB

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MBIRA_data_documentation_appendices.pdf
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Documentation
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MBIRA study dataset – supporting documentation
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MBIRA_patient information_child_English.pdf
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Study Instrument
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Combined patient information and consent form - template version (2020-07-03)
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mbira_data.txt
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Data
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Data Sharing Agreement
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Please contact the study authors directly in relation to other study data
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Data-Codebook.html
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Documentation
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MBIRA data codebook
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