Udosen, B, Soremekun, O, Ekenna, C, Idowu Omotuyi, O, Chikowore, T, Nashiru, O and Fatumo, S. 2021. Additional file 1 of In-silico analysis reveals druggable single nucleotide polymorphisms in angiotensin 1 converting enzyme involved in the onset of blood pressure. [Online]. Figshare. Available from: https://doi.org/10.6084/m9.figshare.17305518.v1
Udosen, B, Soremekun, O, Ekenna, C, Idowu Omotuyi, O, Chikowore, T, Nashiru, O and Fatumo, S. Additional file 1 of In-silico analysis reveals druggable single nucleotide polymorphisms in angiotensin 1 converting enzyme involved in the onset of blood pressure [Internet]. Figshare; 2021. Available from: https://doi.org/10.6084/m9.figshare.17305518.v1
Udosen, B, Soremekun, O, Ekenna, C, Idowu Omotuyi, O, Chikowore, T, Nashiru, O and Fatumo, S (2021). Additional file 1 of In-silico analysis reveals druggable single nucleotide polymorphisms in angiotensin 1 converting enzyme involved in the onset of blood pressure. [Data Collection]. Figshare. https://doi.org/10.6084/m9.figshare.17305518.v1
Description
Additional file 1: Table S1. Nonsynonymous Single Nucleotide Polymorphism of ACE1 gene retrieved from NCBI dbSNP database. Table S2. a Deleterious or disease-causing SNPs across the six in silico tools (SNPs&GO, PROVEAN, PhD-SNP, Polyphen-2, PANTHER and SIFT). b SIFT predictive result of deleterious of nsSNPs. c SNPs&GO deleterious nsSNPs prediction. d PROVEAN predictive result of deleterious or disease-causing nsSNPs. e Polyphen-2 predictive result of deleterious or disease-causing nsSNPs. Table S3. a INSP protein stability predictions for nsSNPs in ACE1. b MUpro stability prediction result for MUpro_NN and MUpro_SVM. c I-Mutant prediction result for ACE1 protein stability. d istable server protein stability prediction using MUpro_SVM, MUpro_NN, iPTREE- STAB and I-Mutant. Table S4. Consurf conservation prediction analysis.
| Data capture method | Unknown |
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| Date (Date published in a 3rd party system) | 21 December 2021 |
| Language(s) of written materials | English |
| Data Creators | Udosen, B, Soremekun, O, Ekenna, C, Idowu Omotuyi, O, Chikowore, T, Nashiru, O and Fatumo, S |
|---|---|
| LSHTM Faculty/Department | Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Funders |
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| Date Deposited | 21 Jan 2022 11:36 |
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| Last Modified | 21 Jan 2022 11:36 |
| Publisher | Figshare |
