Plasmodium chabaudi genotype DK parasite stages during time series
Prior, KF; Middleton, B; Owolabi, AT; Westwood, ML; Holland, J; O'Donnell, AJ; Blackman, MJORCID logo; Skene, DJ and Reece, SE (2021). Plasmodium chabaudi genotype DK parasite stages during time series. [Dataset]. Figshare. https://doi.org/10.6084/m9.figshare.14842695.v1
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After infecting mice intravenously with 1×105 P. chabaudi DK genotype infected RBC at ring stage we made a thin blood smear on day 5 post infection and again every 2 hours to quantify parasite rhythms by counting ~100 parasites where possible per blood smear using compound microscopy. Following (Prior et al 2018, O’Donnell et al 2019 and Rijo-Ferreira et al 2020), we used the proportion of ring stages as a phase marker (an estimate of the timing of parasite development in the blood) of parasite rhythms.

Keywords

Plasmodium; Periodicity; Circadian rhythm; Metabolism; Metabolomics; Isoleucine; Asexual replication

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