Plasmodium chabaudi genotype DK parasite stages during time series
Prior, KF; Middleton, B; Owolabi, AT; Westwood, ML; Holland, J; O'Donnell, AJ; Blackman, MJ
; Skene, DJ and Reece, SE
(2021).
Plasmodium chabaudi genotype DK parasite stages during time series.
[Dataset].
Figshare.
https://doi.org/10.6084/m9.figshare.14842695.v1
; Skene, DJ and Reece, SE
(2021).
Plasmodium chabaudi genotype DK parasite stages during time series.
[Dataset].
Figshare.
https://doi.org/10.6084/m9.figshare.14842695.v1
After infecting mice intravenously with 1×105 P. chabaudi DK genotype infected RBC at ring stage we made a thin blood smear on day 5 post infection and again every 2 hours to quantify parasite rhythms by counting ~100 parasites where possible per blood smear using compound microscopy. Following (Prior et al 2018, O’Donnell et al 2019 and Rijo-Ferreira et al 2020), we used the proportion of ring stages as a phase marker (an estimate of the timing of parasite development in the blood) of parasite rhythms.
Keywords
Plasmodium; Periodicity; Circadian rhythm; Metabolism; Metabolomics; Isoleucine; Asexual replication| Item Type | Dataset |
|---|---|
| Resource Type |
Resource Type Resource Description Dataset Quantitative |
| Capture method | Experiment |
| Date | 27 June 2021 |
| Language(s) of written materials | English |
| Creator(s) |
Prior, KF; Middleton, B; Owolabi, AT; Westwood, ML; Holland, J; O'Donnell, AJ; Blackman, MJ; Skene, DJ and Reece, SE
|
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Immunology and Infection (-2019) |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Date Deposited | 01 Dec 2021 13:27 |
| Last Modified | 01 Dec 2021 13:27 |
| Publisher | Figshare |
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