Blood glucose concentration time series in mice infected with malaria parasites
, Skene, DJ and Reece, SE
(2021).
Blood glucose concentration time series in mice infected with malaria parasites.
[Dataset].
Figshare.
https://doi.org/10.6084/m9.figshare.14912709.v2
Experiment 1 (glucose_TS_fs.csv): Blood glucose concentration (mmol/L) from 20 mice every 2 hours on day 5 post infection, with 1×10^5 P. chabaudi DK genotype infected red blood cells by intravenous injection, by taking 1 μl blood using an Accu-Chek Performa Nano glucometer (https://www.accu-chek.co.uk/blood-glucose-meters/performa- nano).
Experiment 2 (Glucose_expt2_fs.csv): Intra-peritoneal injections of glucose (3g/kg, n=5), glucose + insulin (4.5IU/kg insulin + 3g/kg glucose, n=6) or PBS (n=5) occurring every 24 hours after infection with 1×10^5 P. chabaudi DK genotype infected red blood cells. Mice sampled every 4h days 5-6 post infection for parasite density, glucose concentration, RBC density.
Keywords
Plasmodium, Blood glucose, Periodicity, Circadian rhythm, Metabolism, Metabolomics, Asexual replication| Item Type | Dataset |
|---|---|
| Capture method | Experiment |
| Date | 8 October 2021 |
| Language(s) of written materials | English |
| Creator(s) |
Prior, KF, Middleton, B, Owolabi, AT, Westwood, ML, Holland, J, O'Donnell, AJ, Blackman, MJ, Skene, DJ and Reece, SE
|
| LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Immunology and Infection (-2019) |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Date Deposited | 01 Dec 2021 13:12 |
| Last Modified | 01 Dec 2021 13:12 |
| Publisher | Figshare |
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