Data for: “BCG revaccination in Malawi: 30-year follow-up of a large, randomised, double-blind placebo-controlled trial”

Glynn, JR, Fielding, K, Mzembe, T, Sichali, L, Banda, L, Mclean, E, Kanjala, C, Crampin, AC, Ponnighaus, J, Warndorff, D and Fine, P. 2021. Data for: “BCG revaccination in Malawi: 30-year follow-up of a large, randomised, double-blind placebo-controlled trial”. [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: https://doi.org/10.17037/DATA.00002443.

Glynn, JR, Fielding, K, Mzembe, T, Sichali, L, Banda, L, Mclean, E, Kanjala, C, Crampin, AC, Ponnighaus, J, Warndorff, D and Fine, P. Data for: “BCG revaccination in Malawi: 30-year follow-up of a large, randomised, double-blind placebo-controlled trial” [Internet]. London School of Hygiene & Tropical Medicine; 2021. Available from: https://doi.org/10.17037/DATA.00002443.

Glynn, JR, Fielding, K, Mzembe, T, Sichali, L, Banda, L, Mclean, E, Kanjala, C, Crampin, AC, Ponnighaus, J, Warndorff, D and Fine, P (2021). Data for: “BCG revaccination in Malawi: 30-year follow-up of a large, randomised, double-blind placebo-controlled trial”. [Data Collection]. London School of Hygiene & Tropical Medicine, London, United Kingdom. https://doi.org/10.17037/DATA.00002443.

Description

Additional information

Description of data capture Individuals age 3 months to 75 years were recruited in house-to-house surveys in 1986-89 in Karonga District, northern Malawi. Those with a BCG scar were randomised to receive repeat BCG or placebo. Those without a BCG scar were randomised to receive BGG or a combined BCG + killed M leprae vaccine. Surveillance was by a mixture of active and passive surveillance. The original trial methods and results after 5-9 years follow-up are described in detail in: [1] Ponnighaus JM, Fine PEM, Bliss L, et al. The Karonga Prevention Trial: A leprosy and tuberculosis vaccine trial in Northern Malawi - I: Methods of the vaccination phase. Lepr Rev 1993; 64: 338-56. [2] Karonga Prevention Trial Group. Randomised controlled trial of single BCG, repeated BCG, or combined BCG and killed Mycobacterium leprae vaccine for prevention of leprosy and tuberculosis in Malawi. Lancet 1996; 348: 17-24.
Data capture method Questionnaire: Fixed form - Paper, Measurements and tests
Data Collection Period
FromTo
January 1986December 2018
Date (Completed) 12 August 2021
Geographical area covered
North LatitudeEast LongitudeSouth LatitudeWest Longitude
-9.9176333.938-10.012333.8817
Language(s) of written materials English
Data Creators Glynn, JR, Fielding, K, Mzembe, T, Sichali, L, Banda, L, Mclean, E, Kanjala, C, Crampin, AC, Ponnighaus, J, Warndorff, D and Fine, P
LSHTM Faculty/Department Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Group MEIRU (Malawi Epidemiology and Intervention Research Unit)
Participating Institutions London School of Hygiene & Tropical Medicine, London, United Kingdom, MEIRU (Malawi Epidemiology and Intervention Research Unit)
Funders
ProjectFunderGrant NumberFunder URI
Karonga Prevention TrialBritish Leprosy Relief Association (LEPRA)UNSPECIFIEDUNSPECIFIED
Karonga Prevention TrialInternational Federation of Anti-Leprosy Organizations (ILEP)UNSPECIFIEDUNSPECIFIED
Karonga Prevention TrialGlaxoSmithKlineUNSPECIFIEDhttp://dx.doi.org/10.13039/100004330
Karonga Prevention TrialUNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (IMMLEP/TDR)UNSPECIFIEDUNSPECIFIED
Karonga Prevention TrialWellcome Trust063558/01, 079827/06, 098610/12http://dx.doi.org/10.13039/100010269
Karonga Prevention TrialBill and Melinda Gates FoundationOPP1210686http://dx.doi.org/10.13039/100000865
Date Deposited 12 Aug 2021 11:43
Last Modified 20 Aug 2021 15:28
Publisher London School of Hygiene & Tropical Medicine

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