Data for: “BCG revaccination in Malawi: 30-year follow-up of a large, randomised, double-blind placebo-controlled trial”

Glynn, JR, Fielding, K, Mzembe, T, Sichali, L, Banda, L, Mclean, E, Kanjala, C, Crampin, AC, Ponnighaus, J, Warndorff, D and Fine, P. 2021. Data for: “BCG revaccination in Malawi: 30-year follow-up of a large, randomised, double-blind placebo-controlled trial”. [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: https://doi.org/10.17037/DATA.00002443.

Glynn, JR, Fielding, K, Mzembe, T, Sichali, L, Banda, L, Mclean, E, Kanjala, C, Crampin, AC, Ponnighaus, J, Warndorff, D and Fine, P. Data for: “BCG revaccination in Malawi: 30-year follow-up of a large, randomised, double-blind placebo-controlled trial” [Internet]. London School of Hygiene & Tropical Medicine; 2021. Available from: https://doi.org/10.17037/DATA.00002443.

Glynn, JR, Fielding, K, Mzembe, T, Sichali, L, Banda, L, Mclean, E, Kanjala, C, Crampin, AC, Ponnighaus, J, Warndorff, D and Fine, P (2021). Data for: “BCG revaccination in Malawi: 30-year follow-up of a large, randomised, double-blind placebo-controlled trial”. [Data Collection]. London School of Hygiene & Tropical Medicine, London, United Kingdom. https://doi.org/10.17037/DATA.00002443.

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Description of data capture Individuals age 3 months to 75 years were recruited in house-to-house surveys in 1986-89 in Karonga District, northern Malawi. Those with a BCG scar were randomised to receive repeat BCG or placebo. Those without a BCG scar were randomised to receive BGG or a combined BCG + killed M leprae vaccine. Surveillance was by a mixture of active and passive surveillance. The original trial methods and results after 5-9 years follow-up are described in detail in: [1] Ponnighaus JM, Fine PEM, Bliss L, et al. The Karonga Prevention Trial: A leprosy and tuberculosis vaccine trial in Northern Malawi - I: Methods of the vaccination phase. Lepr Rev 1993; 64: 338-56. [2] Karonga Prevention Trial Group. Randomised controlled trial of single BCG, repeated BCG, or combined BCG and killed Mycobacterium leprae vaccine for prevention of leprosy and tuberculosis in Malawi. Lancet 1996; 348: 17-24.
Data capture method Questionnaire: Fixed form - Paper, Measurements and tests
Data Collection Period
FromTo
January 1986December 2018
Date (Date submitted to LSHTM repository) 12 August 2021
Geographical area covered (offline during plugin upgrade)
North LatitudeEast LongitudeSouth LatitudeWest Longitude
-9.9176333.938-10.012333.8817
Language(s) of written materials English
Data Creators Glynn, JR, Fielding, K, Mzembe, T, Sichali, L, Banda, L, Mclean, E, Kanjala, C, Crampin, AC, Ponnighaus, J, Warndorff, D and Fine, P
LSHTM Faculty/Department Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Group MEIRU (Malawi Epidemiology and Intervention Research Unit)
Participating Institutions London School of Hygiene & Tropical Medicine, London, United Kingdom, MEIRU (Malawi Epidemiology and Intervention Research Unit)
Funders
ProjectFunderGrant NumberFunder URI
Karonga Prevention TrialBritish Leprosy Relief Association (LEPRA)UNSPECIFIEDUNSPECIFIED
Karonga Prevention TrialInternational Federation of Anti-Leprosy Organizations (ILEP)UNSPECIFIEDUNSPECIFIED
Karonga Prevention TrialGlaxoSmithKlineUNSPECIFIEDhttp://dx.doi.org/10.13039/100004330
Karonga Prevention TrialUNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (IMMLEP/TDR)UNSPECIFIEDUNSPECIFIED
Karonga Prevention TrialWellcome Trust063558/01, 079827/06, 098610/12http://dx.doi.org/10.13039/100010269
Karonga Prevention TrialBill and Melinda Gates FoundationOPP1210686http://dx.doi.org/10.13039/100000865
Date Deposited 12 Aug 2021 11:43
Last Modified 01 Feb 2022 17:47
Publisher London School of Hygiene & Tropical Medicine

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