Cresswell, F and Quinn, C. 2021. Neurocognitive outcomes of HIV-associated tuberculous meningitis dataset. [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: https://doi.org/10.17037/DATA.00002372.
Cresswell, F and Quinn, C. Neurocognitive outcomes of HIV-associated tuberculous meningitis dataset [Internet]. London School of Hygiene & Tropical Medicine; 2021. Available from: https://doi.org/10.17037/DATA.00002372.
Cresswell, F and Quinn, C (2021). Neurocognitive outcomes of HIV-associated tuberculous meningitis dataset. [Data Collection]. London School of Hygiene & Tropical Medicine, London, United Kingdom. https://doi.org/10.17037/DATA.00002372.
Description
Data collected as part of the “High dose oral and intravenous rifampicin for improved survival from adult tuberculous meningitis” (RIFT) study, a phase 2 open-label randomized trial (ISRCTN42218549). It contains information obtained from 36 patients who were diagnosed with TB meningitis and enrolled between January 14 and December 17, 2019 at Kiruddu National Referral Hospital in Kampala, Uganda. Variables include baseline clinical and laboratory results, as well as clinical statuses, functional statuses, results of depression screening, and detailed neurocognitive assessment of across motor and cognitive domains at 8 and 24 weeks of follow up. Results of neurocognitive tests are reported both as raw scores and as Z-scores standardized to a cohort of HIV-negative Ugandan age- and education-matched controls. Data access is restricted in compliance with conditions outlined in the study protocol and ethics approvals. Data will only be shared with researchers and doctors for use in limited conditions (e.g. to inform dosage and route of administration of rifampicin) and requires written approval by the Institutional Review Board (IRB) or study sponsor.
Additional information
Data access is restricted in compliance with conditions outlined in the study protocol and ethics approvals. Data will only be shared with researchers and doctors for use in limited conditions (to inform dosage and route of administration of rifampicin) and requires written approval by the Institutional Review Board (IRB) or study sponsor.
Keywords
Data capture method | Physical measurements and tests |
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Date (Date submitted to LSHTM repository) | 15 July 2021 |
Language(s) of written materials | English |
Data Creators | Cresswell, F and Quinn, C |
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LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Clinical Research |
Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom, Infectious Diseases Institute, Kampala, Uganda |
Funders |
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Date Deposited | 26 Jul 2021 15:44 |
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Last Modified | 27 Oct 2021 11:23 |
Publisher | London School of Hygiene & Tropical Medicine |
Downloads
Data / Code
Restricted to: Request access for all
Filename: Neurocognitive_dataset.csv
Description: Neurocognitive dataset - consult description for access conditions
Licence: Data Sharing Agreement
Content type: Dataset
File size: 29B
Mime-Type: text/plain
Documentation
Filename: Neurocognitive_dataset_codebook.html
Description: Codebook for Neurocognitive dataset
Content type: Textual content
File size: 14kB
Mime-Type: text/html