A dataset of human and Plasmodium falciparum genotypes in severe malaria cases from The Gambia and Kenya

Band, G, Leffler, EM, Jallow, M, Sisay-Joof, F, Ndila, CM, Macharia, AW, Hubbart, C, Jeffreys, AE, Rowlands, K, Nguyen, T, Goncalves, SM, Ariani, CV, Stalker, J, Pearson, RD, Amato, R, Drury, E, Sirugo, G, D'Alessandro, U, Bojang, KA, Marsh, K, Peshu, N, Conway, DJ, Williams, TN, Rockett, KA and Kwiatkowski, DP. 2021. A dataset of human and Plasmodium falciparum genotypes in severe malaria cases from The Gambia and Kenya. [Online]. Zenodo. Available from: https://doi.org/10.5281/zenodo.4973476

Band, G, Leffler, EM, Jallow, M, Sisay-Joof, F, Ndila, CM, Macharia, AW, Hubbart, C, Jeffreys, AE, Rowlands, K, Nguyen, T, Goncalves, SM, Ariani, CV, Stalker, J, Pearson, RD, Amato, R, Drury, E, Sirugo, G, D'Alessandro, U, Bojang, KA, Marsh, K, Peshu, N, Conway, DJ, Williams, TN, Rockett, KA and Kwiatkowski, DP. A dataset of human and Plasmodium falciparum genotypes in severe malaria cases from The Gambia and Kenya [Internet]. Zenodo; 2021. Available from: https://doi.org/10.5281/zenodo.4973476

Band, G, Leffler, EM, Jallow, M, Sisay-Joof, F, Ndila, CM, Macharia, AW, Hubbart, C, Jeffreys, AE, Rowlands, K, Nguyen, T, Goncalves, SM, Ariani, CV, Stalker, J, Pearson, RD, Amato, R, Drury, E, Sirugo, G, D'Alessandro, U, Bojang, KA, Marsh, K, Peshu, N, Conway, DJ, Williams, TN, Rockett, KA and Kwiatkowski, DP (2021). A dataset of human and Plasmodium falciparum genotypes in severe malaria cases from The Gambia and Kenya. [Data Collection]. Zenodo. https://doi.org/10.5281/zenodo.4973476

Description

This data release accompanies the article “The protective effect of sickle cell haemoglobin depends on parasite genotype” which is currently under review and is available in preprint form at https://doi.org/10.1101/2021.03.30.437659. The release contains genotypes from human and Plasmodium falciparum genetic variants, genotyped using blood samples from 4,171 children ascertained with severe symptoms of malaria at the Royal Victoria Teaching Hospital (now the Edward Francis Small Teaching Hospital), The Gambia, and from the Kilifi District Hospital (now Kilifi County Hospital), Kenya in the period 1995-2009.

Methods

Data capture method	Experiment: Field Intervention
Date (Date published in a 3rd party system)	17 June 2021
Language(s) of written materials	English

People & Groups

Data Creators	Band, G, Leffler, EM, Jallow, M, Sisay-Joof, F, Ndila, CM, Macharia, AW, Hubbart, C, Jeffreys, AE, Rowlands, K, Nguyen, T, Goncalves, SM, Ariani, CV, Stalker, J, Pearson, RD, Amato, R, Drury, E, Sirugo, G, D'Alessandro, U, Bojang, KA, Marsh, K, Peshu, N, Conway, DJ, Williams, TN, Rockett, KA and Kwiatkowski, DP
LSHTM Faculty/Department	MRC Unit The Gambia at LSHTM
Participating Institutions	London School of Hygiene & Tropical Medicine, London, United Kingdom