ParisBap/TTE_ONTARGET

Baptiste, PJORCID logo (2024). ParisBap/TTE_ONTARGET. [Dataset]. Github. https://github.com/ParisBap/TTE_ONTARGET/
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Programming code and code lists used for project using the ONTARGET trial to inform design and benchmark findings before extending results to explore treatment heterogeneity by ethnicity using CPRD Aurum-linked data Study applies reference trial emulation methods to (1) emulate the design of and; (2) benchmark findings against an existing RCT (ONTARGET) before extending analysis to explore treatment effect heterogeneity by ethnicity. Explores treatment effects of ARB vs ACEi among an ONTARGET-eligible cohort in CPRD Aurum-linked data. Code lists include product codes used to define exposure of ARB of ACEi. ICD10, OPCS and medcodes used to emulate the inclusion and exclusion criteria from the ONTARGET trial using CPRD-linked data and codes used to define outcomes. Do-files include data management files, analysis files and do-files used to build propensity score models.

Keywords

Ethnicities; Cardiovascular therapy; Myocardial infarction; Cardiovascular disease risk; Chronic kidney disease; Blood pressure; Glomerular filtration rate; Ethnic epidemiology

Item Type Dataset
Resource Type
Resource Type
Resource Description
Dataset
Codelists and Stata Do files
Capture method Other
Date 19 July 2024
Language(s) of written materials English
Creator(s) Baptiste, PJORCID logo
LSHTM Faculty/Department Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology
Participating Institutions London School of Hygiene & Tropical Medicine, London, United Kingdom
Funders
Project
Funder
Grant Number
Funder URI
Effectiveness and risk of ARB and ACEi among different ethnic groups in England: A reference trial (ONTARGET) emulation analysis using UK Clinical Practice Research Datalink Aurum-linked data
Wellcome Trust
224485/Z/21/Z
http://dx.doi.org/10.13039/100010269
UNSPECIFIED
GlaxoSmithKline
UNSPECIFIED
http://dx.doi.org/10.13039/100004330
Date Deposited 26 Sep 2024 11:20
Last Modified 06 Feb 2026 10:15
Publisher Github

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