ParisBap/TTE_ONTARGET
(2024).
ParisBap/TTE_ONTARGET.
[Dataset].
Github.
https://github.com/ParisBap/TTE_ONTARGET/
Programming code and code lists used for project using the ONTARGET trial to inform design and benchmark findings before extending results to explore treatment heterogeneity by ethnicity using CPRD Aurum-linked data
Study applies reference trial emulation methods to (1) emulate the design of and; (2) benchmark findings against an existing RCT (ONTARGET) before extending analysis to explore treatment effect heterogeneity by ethnicity. Explores treatment effects of ARB vs ACEi among an ONTARGET-eligible cohort in CPRD Aurum-linked data. Code lists include product codes used to define exposure of ARB of ACEi. ICD10, OPCS and medcodes used to emulate the inclusion and exclusion criteria from the ONTARGET trial using CPRD-linked data and codes used to define outcomes. Do-files include data management files, analysis files and do-files used to build propensity score models.
Keywords
Ethnicities, Cardiovascular therapy, Myocardial infarction, Cardiovascular disease risk, Chronic kidney disease, Blood pressure, Glomerular filtration rate, Ethnic epidemiology| Item Type | Dataset |
|---|---|
| Capture method | Other |
| Date | 19 July 2024 |
| Language(s) of written materials | English |
| Creator(s) |
Baptiste, PJ
|
| LSHTM Faculty/Department | Faculty of Epidemiology and Population Health > Dept of Non-Communicable Disease Epidemiology |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Funders |
Project Funder Grant Number Funder URI Effectiveness and risk of ARB and ACEi among different ethnic groups in England: A reference trial (ONTARGET) emulation analysis using UK Clinical Practice Research Datalink Aurum-linked data 224485/Z/21/Z http://dx.doi.org/10.13039/100010269 |
| Date Deposited | 26 Sep 2024 11:20 |
| Last Modified | 27 Sep 2024 08:31 |
| Publisher | Github |
No files available. Please consult associated links.
