Adjunctive host-directed therapies for pulmonary tuberculosis: data from a prospective, open-label, phase 2, randomised controlled trial

Fielding, KORCID logo (2021). Adjunctive host-directed therapies for pulmonary tuberculosis: data from a prospective, open-label, phase 2, randomised controlled trial. [Dataset]. London School of Hygiene & Tropical Medicine, London, United Kingdom. 10.17037/DATA.00002277.
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The dataset was produced as part of a phase 2 randomised controlled trial of adults with pulmonary tuberculosis, conducted in South Africa (ClinicalTrials.gov, NCT02968927). It consists of 9 data tables from n=199 participants, randomised and who had taken at least one dose of treatment: [1] Adverse Event (AE) data, [2] Baseline data, [3] CRP measurement data, [4] Sputum culture results data, [5] PET CT Scan data, [6] Pulmonary Function Test (PFT) data, [7] Randomisation data, [8] Visit timings data, and [9] Whole blood assay (WBA) data.

Additional Information

Trial investigators and participants are committed to making anonymized patient-level data from this trial available to qualified researchers in a timely manner. Please contact us, including a description of the proposed research and your background, to begin this process.

Keywords

randomised control trials; Pulmonary Tuberculosis

Item Type Dataset
Resource Type
Resource Type
Resource Description
Dataset
Quantitative
Capture method Measurements and tests
Collection Period
From
To
November 2016
April 2020
Date 31 August 2021
Language(s) of written materials English
Creator(s) Fielding, KORCID logo
Associated roles Wallis, R (Principal Investigator)
LSHTM Faculty/Department Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology (-2023)
Research Centre TB Centre
Participating Institutions London School of Hygiene & Tropical Medicine, London, United Kingdom; The Aurum Institute, Johannesburg, 2194, South Africa
Funders
Project
Funder
Grant Number
Funder URI
TB Host Directed Therapy (TBHDT)
Bill and Melinda Gates Foundation
OPP1127276–2015
http://dx.doi.org/10.13039/100000865
TB Host Directed Therapy (TBHDT)
South African Medical Research Council
ACT4TB/HIV
http://dx.doi.org/10.13039/501100001322
Date Deposited 15 Sep 2021 16:08
Last Modified 23 Oct 2025 13:59
Publisher London School of Hygiene & Tropical Medicine

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HDT Study dataset collection - see codebook for information
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