Data for: "Association between Female Genital Schistosomiasis and HIV-1 incidence: a retrospective cohort study"

Sturt, A. 2021. Data for: "Association between Female Genital Schistosomiasis and HIV-1 incidence: a retrospective cohort study". [Online]. London School of Hygiene & Tropical Medicine, London, United Kingdom. Available from: https://doi.org/10.17037/DATA.00001927.

Sturt, A. Data for: "Association between Female Genital Schistosomiasis and HIV-1 incidence: a retrospective cohort study" [Internet]. London School of Hygiene & Tropical Medicine; 2021. Available from: https://doi.org/10.17037/DATA.00001927.

Sturt, A (2021). Data for: "Association between Female Genital Schistosomiasis and HIV-1 incidence: a retrospective cohort study". [Data Collection]. London School of Hygiene & Tropical Medicine, London, United Kingdom. https://doi.org/10.17037/DATA.00001927.

Description

The longitudinal follow-up of women in the HPTN 071 (PopART) trial in two schistosomiasis-endemic communities in Zambia provided an opportunity for a nested study of the association of Female Genital Schistosomiasis (FGS) with HIV-1 incidence. In the bilharzia and HIV (BILHIV) study, we conducted an array of diagnostic tests for S. haematobium infection and FGS, demonstrating that self-collected genital swabs had comparable sensitivity to clinic-based, midwife-collected CVL for the detection of Schistosoma DNA by real-time PCR. HIV-1 outcomes were available for the HPTN 071 (PopART) Population Cohort at final follow-up. BILHIV study participants were consecutively recruited from the Population Cohort, providing the opportunity to compare the rate of incident HIV-1 infection in women with and without FGS, with power ultimately determined by the number of HIV seroconversion events in this nested study.

Methods

Description of data capture

The home visit included assessment of eligibility, a questionnaire, genital self-sampling (cervical and vaginal), and a single urine specimen. Questionnaire data were captured on tablets using Open Data Kit.

Data capture method

Questionnaire

Data Collection Period

From	To
8 January 2018	31 August 2018

Date (Date submitted to LSHTM repository)

10 June 2021

Geographical area covered (offline during plugin upgrade)

North Latitude	East Longitude	South Latitude	West Longitude
-17.6932	26.2018	-17.9912	25.6806

Language(s) of written materials

English

People & Groups

Data Creators	Sturt, A
Associated roles	Sturt, A (Data Manager), Bustinduy, A (Principal Investigator) and Webb, E (Researcher)
LSHTM Faculty/Department	Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Participating Institutions	London School of Hygiene & Tropical Medicine, London, United Kingdom