Data for: "Association between Female Genital Schistosomiasis and HIV-1 incidence: a retrospective cohort study"

Sturt, A

(2021). Data for: "Association between Female Genital Schistosomiasis and HIV-1 incidence: a retrospective cohort study". [Dataset]. London School of Hygiene & Tropical Medicine, London, United Kingdom. 10.17037/DATA.00001927.

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The longitudinal follow-up of women in the HPTN 071 (PopART) trial in two schistosomiasis-endemic communities in Zambia provided an opportunity for a nested study of the association of Female Genital Schistosomiasis (FGS) with HIV-1 incidence. In the bilharzia and HIV (BILHIV) study, we conducted an array of diagnostic tests for S. haematobium infection and FGS, demonstrating that self-collected genital swabs had comparable sensitivity to clinic-based, midwife-collected CVL for the detection of Schistosoma DNA by real-time PCR. HIV-1 outcomes were available for the HPTN 071 (PopART) Population Cohort at final follow-up. BILHIV study participants were consecutively recruited from the Population Cohort, providing the opportunity to compare the rate of incident HIV-1 infection in women with and without FGS, with power ultimately determined by the number of HIV seroconversion events in this nested study.

Keywords

Female Genital Schistosomiasis; HIV; Incidence

Item Type	Dataset
Resource Type	Resource Type Resource Description Dataset Quantitative
Description of data capture	The home visit included assessment of eligibility, a questionnaire, genital self-sampling (cervical and vaginal), and a single urine specimen. Questionnaire data were captured on tablets using Open Data Kit.
Capture method	Questionnaire
Collection Period	From To 8 January 2018 31 August 2018
Date	10 June 2021
Geographical area covered (offline during plugin upgrade)	North East South West -17.6932 26.2018 -17.9912 25.6806
Language(s) of written materials	English
Creator(s)	Sturt, A
Associated roles	Sturt, A (Data Manager); Bustinduy, A (Principal Investigator) and Webb, E (Researcher)
LSHTM Faculty/Department	Faculty of Infectious and Tropical Diseases > Dept of Clinical Research
Participating Institutions	London School of Hygiene & Tropical Medicine, London, United Kingdom
Funders	Project Funder Grant Number Funder URI The BILHIV study Wellcome Trust UNSPECIFIED http://dx.doi.org/10.13039/100010269
Date Deposited	29 Jun 2021 11:29
Last Modified	30 Oct 2025 15:04
Publisher	London School of Hygiene & Tropical Medicine