Data for: "Association between Female Genital Schistosomiasis and HIV-1 incidence: a retrospective cohort study"

Sturt, AORCID logo (2021). Data for: "Association between Female Genital Schistosomiasis and HIV-1 incidence: a retrospective cohort study". [Dataset]. London School of Hygiene & Tropical Medicine, London, United Kingdom. 10.17037/DATA.00001927.
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The longitudinal follow-up of women in the HPTN 071 (PopART) trial in two schistosomiasis-endemic communities in Zambia provided an opportunity for a nested study of the association of Female Genital Schistosomiasis (FGS) with HIV-1 incidence. In the bilharzia and HIV (BILHIV) study, we conducted an array of diagnostic tests for S. haematobium infection and FGS, demonstrating that self-collected genital swabs had comparable sensitivity to clinic-based, midwife-collected CVL for the detection of Schistosoma DNA by real-time PCR. HIV-1 outcomes were available for the HPTN 071 (PopART) Population Cohort at final follow-up. BILHIV study participants were consecutively recruited from the Population Cohort, providing the opportunity to compare the rate of incident HIV-1 infection in women with and without FGS, with power ultimately determined by the number of HIV seroconversion events in this nested study.

Keywords

Female Genital Schistosomiasis, HIV, Incidence

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