Data for: "Association between Female Genital Schistosomiasis and HIV-1 incidence: a retrospective cohort study"
The longitudinal follow-up of women in the HPTN 071 (PopART) trial in two schistosomiasis-endemic communities in Zambia provided an opportunity for a nested study of the association of Female Genital Schistosomiasis (FGS) with HIV-1 incidence. In the bilharzia and HIV (BILHIV) study, we conducted an array of diagnostic tests for S. haematobium infection and FGS, demonstrating that self-collected genital swabs had comparable sensitivity to clinic-based, midwife-collected CVL for the detection of Schistosoma DNA by real-time PCR. HIV-1 outcomes were available for the HPTN 071 (PopART) Population Cohort at final follow-up. BILHIV study participants were consecutively recruited from the Population Cohort, providing the opportunity to compare the rate of incident HIV-1 infection in women with and without FGS, with power ultimately determined by the number of HIV seroconversion events in this nested study.
Keywords
Female Genital Schistosomiasis, HIV, IncidenceItem Type | Dataset |
---|---|
Description of data capture | The home visit included assessment of eligibility, a questionnaire, genital self-sampling (cervical and vaginal), and a single urine specimen. Questionnaire data were captured on tablets using Open Data Kit. |
Capture method | Questionnaire |
Collection Period |
From To 8 January 2018 31 August 2018 |
Date | 10 June 2021 |
Geographical area covered (offline during plugin upgrade) |
North Latitude East Longitude South Latitude West Longitude -17.6932 26.2018 -17.9912 25.6806 |
Language(s) of written materials | English |
Creator(s) |
Sturt, A |
Associated roles | Sturt, A (Data Manager), Bustinduy, A (Principal Investigator) and Webb, E (Researcher) |
LSHTM Faculty/Department | Faculty of Infectious and Tropical Diseases > Dept of Clinical Research |
Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
Funders |
Project Funder Grant Number Funder URI |
Date Deposited | 29 Jun 2021 11:29 |
Last Modified | 29 Jun 2021 15:06 |
Publisher | London School of Hygiene & Tropical Medicine |
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subject - Data
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lock - Restricted to Request access for all
- Data Sharing Agreement
- Available under Data Sharing Agreement
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info - HIV Incidence in FGS dataset
description - text/plain
- folder_info
- 91B
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subject - Documentation
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Codebook for FGS-HIV dataset
html - text/html
- folder_info
- 17kB
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subject - Documentation
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - User guide for HIV Incidence in FGS dataset
html - text/html
- folder_info
- 6kB
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subject - Documentation
- Creative Commons: Attribution
- Available under Creative Commons: Attribution 3.0
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info - Study consent form
picture_as_pdf - application/pdf
- folder_info
- 154kB