Data from: Evolution and epidemic spread of SARS-CoV-2 in Brazil
, Nicholls, SM, Tanuri, A, Rossi, ÁD, Braga, CK, Gerber, AL, de C. Guimarães, AP, Gaburo, N, Alencar, CS, Ferreira, AC, Lima, CX, Levi, JE, Granato, C, Ferreira, GM, Francisco, RS, Granja, F, Garcia, MT, Moretti, ML, Perroud, MW, Castiñeiras, Terezinha M. P. P., Lazari, CS, Hill, SC, de Souza Santos, AA, Simeoni, CL, Forato, J, Sposito, AC, Schreiber, AZ, Santos, MNN, de Sá, CZ, Souza, RP, Resende-Moreira, LC, Teixeira, MM, Hubner, J, Leme, PAF, Moreira, RG, Nogueira, ML, Ferguson, NM, Costa, SF, Proenca-Modena, JL, Vasconcelos, ATR, Bhatt, S, Lemey, P, Wu, C, Rambaut, A, Loman, NJ, Aguiar, RS, Pybus, OG, Sabino, EC and Faria, NR
(2020).
Data from: Evolution and epidemic spread of SARS-CoV-2 in Brazil.
[Dataset].
Dryad.
http://doi.org/10.5061/dryad.rxwdbrv5z
Brazil currently has one of the fastest growing SARS-CoV-2 epidemics in the world. Owing to limited available data, assessments of the impact of non-pharmaceutical interventions (NPIs) on virus spread remain challenging. Using a mobility-driven transmission model, we show that NPIs reduced the reproduction number from >3 to 1–1.6 in São Paulo and Rio de Janeiro. Sequencing of 427 new genomes and analysis of a geographically representative genomic dataset identified >100 international virus introductions in Brazil. We estimate that most (76%) of the Brazilian strains fell in three clades that were introduced from Europe between 22 February11 March 2020. During the early epidemic phase, we found that SARS-CoV-2 spread mostly locally and within-state borders. After this period, despite sharp decreases in air travel, we estimated multiple exportations from large urban centers that coincided with a 25% increase in average travelled distances in national flights. This study sheds new light on the epidemic transmission and evolutionary trajectories of SARS-CoV-2 lineages in Brazil, and provide evidence that current interventions remain insufficient to keep virus transmission under control in the country.
Keywords
SARS-CoV-2, COVID-19, Coronavirus, Non-pharmaceutical interventions| Item Type | Dataset |
|---|---|
| Capture method | Unknown |
| Date | 5 August 2020 |
| Language(s) of written materials | English |
| Creator(s) |
Candido, DS, Claro, IM, de Jesus, JG, Souza, WM, Moreira, FRR, Dellicour, S, Mellan, TA, du Plessis, L, Pereira, RHM, Sales, FCS, Manuli, ER, Thézé, J, Almeida, L, Menezes, MT, Voloch, CM, Fumagalli, MJ, Coletti, TM, da Silva, CAM, Ramundo, MS, Amorim, MR, Hoeltgebaum, HH, Mishra, S, Gill, MS, Carvalho, LM, Buss, LF, Prete, CA, Ashworth, J, Nakaya, HI, Peixoto, PS, Brady, OJ, Nicholls, SM, Tanuri, A, Rossi, ÁD, Braga, CK, Gerber, AL, de C. Guimarães, AP, Gaburo, N, Alencar, CS, Ferreira, AC, Lima, CX, Levi, JE, Granato, C, Ferreira, GM, Francisco, RS, Granja, F, Garcia, MT, Moretti, ML, Perroud, MW, Castiñeiras, Terezinha M. P. P., Lazari, CS, Hill, SC, de Souza Santos, AA, Simeoni, CL, Forato, J, Sposito, AC, Schreiber, AZ, Santos, MNN, de Sá, CZ, Souza, RP, Resende-Moreira, LC, Teixeira, MM, Hubner, J, Leme, PAF, Moreira, RG, Nogueira, ML, Ferguson, NM, Costa, SF, Proenca-Modena, JL, Vasconcelos, ATR, Bhatt, S, Lemey, P, Wu, C, Rambaut, A, Loman, NJ, Aguiar, RS, Pybus, OG, Sabino, EC and Faria, NR
|
| LSHTM Faculty/Department | Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology (-2023) |
| Participating Institutions | London School of Hygiene & Tropical Medicine, London, United Kingdom |
| Funders |
Project Funder Grant Number Funder URI |
| Date Deposited | 24 Aug 2020 13:10 |
| Last Modified | 08 Jul 2021 12:49 |
| Publisher | Dryad |
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